Probing the impact of sulfur/selenium/carbon linkages on prodrug nanoassemblies for cancer therapy

Prodrug-based self-assembled nanoparticles have emerged as an efficient drug delivery system (DDS) for cancer therapy. Here, the authors show that the type of bond in prodrug assemblies influences the efficiency of the DDS on several different levels.

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Autores principales: Bingjun Sun, Cong Luo, Xuanbo Zhang, Mengran Guo, Mengchi Sun, Han Yu, Qin Chen, Wenqian Yang, Menglin Wang, Shiyi Zuo, Pengyu Chen, Qiming Kan, Haotian Zhang, Yongjun Wang, Zhonggui He, Jin Sun
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Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/080cae64d81641a5889836efc1dfe3d1
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spelling oai:doaj.org-article:080cae64d81641a5889836efc1dfe3d12021-12-02T14:39:20ZProbing the impact of sulfur/selenium/carbon linkages on prodrug nanoassemblies for cancer therapy10.1038/s41467-019-11193-x2041-1723https://doaj.org/article/080cae64d81641a5889836efc1dfe3d12019-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-11193-xhttps://doaj.org/toc/2041-1723Prodrug-based self-assembled nanoparticles have emerged as an efficient drug delivery system (DDS) for cancer therapy. Here, the authors show that the type of bond in prodrug assemblies influences the efficiency of the DDS on several different levels.Bingjun SunCong LuoXuanbo ZhangMengran GuoMengchi SunHan YuQin ChenWenqian YangMenglin WangShiyi ZuoPengyu ChenQiming KanHaotian ZhangYongjun WangZhonggui HeJin SunNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Bingjun Sun
Cong Luo
Xuanbo Zhang
Mengran Guo
Mengchi Sun
Han Yu
Qin Chen
Wenqian Yang
Menglin Wang
Shiyi Zuo
Pengyu Chen
Qiming Kan
Haotian Zhang
Yongjun Wang
Zhonggui He
Jin Sun
Probing the impact of sulfur/selenium/carbon linkages on prodrug nanoassemblies for cancer therapy
description Prodrug-based self-assembled nanoparticles have emerged as an efficient drug delivery system (DDS) for cancer therapy. Here, the authors show that the type of bond in prodrug assemblies influences the efficiency of the DDS on several different levels.
format article
author Bingjun Sun
Cong Luo
Xuanbo Zhang
Mengran Guo
Mengchi Sun
Han Yu
Qin Chen
Wenqian Yang
Menglin Wang
Shiyi Zuo
Pengyu Chen
Qiming Kan
Haotian Zhang
Yongjun Wang
Zhonggui He
Jin Sun
author_facet Bingjun Sun
Cong Luo
Xuanbo Zhang
Mengran Guo
Mengchi Sun
Han Yu
Qin Chen
Wenqian Yang
Menglin Wang
Shiyi Zuo
Pengyu Chen
Qiming Kan
Haotian Zhang
Yongjun Wang
Zhonggui He
Jin Sun
author_sort Bingjun Sun
title Probing the impact of sulfur/selenium/carbon linkages on prodrug nanoassemblies for cancer therapy
title_short Probing the impact of sulfur/selenium/carbon linkages on prodrug nanoassemblies for cancer therapy
title_full Probing the impact of sulfur/selenium/carbon linkages on prodrug nanoassemblies for cancer therapy
title_fullStr Probing the impact of sulfur/selenium/carbon linkages on prodrug nanoassemblies for cancer therapy
title_full_unstemmed Probing the impact of sulfur/selenium/carbon linkages on prodrug nanoassemblies for cancer therapy
title_sort probing the impact of sulfur/selenium/carbon linkages on prodrug nanoassemblies for cancer therapy
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/080cae64d81641a5889836efc1dfe3d1
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