Single cell transcriptome profiling of retinal ganglion cells identifies cellular subtypes

Retinal ganglion cells (RGCs) are diverse in cellular function and physiology. This study demonstrates additional RGC heterogeneity using single cell transcriptomic analyses to classify 40 classes of RGCs in early postnatal mice before eye opening.

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Autores principales:	Bruce A. Rheaume, Amyeo Jereen, Mohan Bolisetty, Muhammad S. Sajid, Yue Yang, Kathleen Renna, Lili Sun, Paul Robson, Ephraim F. Trakhtenberg
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/08131fcc4f37498a9ef0c48c3484173a
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spelling	oai:doaj.org-article:08131fcc4f37498a9ef0c48c3484173a2021-12-02T17:32:15ZSingle cell transcriptome profiling of retinal ganglion cells identifies cellular subtypes10.1038/s41467-018-05134-32041-1723https://doaj.org/article/08131fcc4f37498a9ef0c48c3484173a2018-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-05134-3https://doaj.org/toc/2041-1723Retinal ganglion cells (RGCs) are diverse in cellular function and physiology. This study demonstrates additional RGC heterogeneity using single cell transcriptomic analyses to classify 40 classes of RGCs in early postnatal mice before eye opening.Bruce A. RheaumeAmyeo JereenMohan BolisettyMuhammad S. SajidYue YangKathleen RennaLili SunPaul RobsonEphraim F. TrakhtenbergNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Bruce A. Rheaume Amyeo Jereen Mohan Bolisetty Muhammad S. Sajid Yue Yang Kathleen Renna Lili Sun Paul Robson Ephraim F. Trakhtenberg Single cell transcriptome profiling of retinal ganglion cells identifies cellular subtypes
description	Retinal ganglion cells (RGCs) are diverse in cellular function and physiology. This study demonstrates additional RGC heterogeneity using single cell transcriptomic analyses to classify 40 classes of RGCs in early postnatal mice before eye opening.
format	article
author	Bruce A. Rheaume Amyeo Jereen Mohan Bolisetty Muhammad S. Sajid Yue Yang Kathleen Renna Lili Sun Paul Robson Ephraim F. Trakhtenberg
author_facet	Bruce A. Rheaume Amyeo Jereen Mohan Bolisetty Muhammad S. Sajid Yue Yang Kathleen Renna Lili Sun Paul Robson Ephraim F. Trakhtenberg
author_sort	Bruce A. Rheaume
title	Single cell transcriptome profiling of retinal ganglion cells identifies cellular subtypes
title_short	Single cell transcriptome profiling of retinal ganglion cells identifies cellular subtypes
title_full	Single cell transcriptome profiling of retinal ganglion cells identifies cellular subtypes
title_fullStr	Single cell transcriptome profiling of retinal ganglion cells identifies cellular subtypes
title_full_unstemmed	Single cell transcriptome profiling of retinal ganglion cells identifies cellular subtypes
title_sort	single cell transcriptome profiling of retinal ganglion cells identifies cellular subtypes
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/08131fcc4f37498a9ef0c48c3484173a
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Single cell transcriptome profiling of retinal ganglion cells identifies cellular subtypes

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