Systematic analysis reveals the prevalence and principles of bypassable gene essentiality

An essential gene may become non-essential when another gene is mutated. Here, the authors investigate this type of digenic interaction, termed ‘bypass of essentiality’, in the fission yeast Schizosaccharomyces pombe, and show that bypassable essential genes are common and share certain features....

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Bibliographic Details
Main Authors: Jun Li, Hai-Tao Wang, Wei-Tao Wang, Xiao-Ran Zhang, Fang Suo, Jing-Yi Ren, Ying Bi, Ying-Xi Xue, Wen Hu, Meng-Qiu Dong, Li-Lin Du
Format: article
Language:EN
Published: Nature Portfolio 2019
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Online Access:https://doaj.org/article/081d51e49b2e42a4b1235dc234b85b81
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