Bacillus subtilis biofilm extends Caenorhabditis elegans longevity through downregulation of the insulin-like signalling pathway

Probiotic bacteria can improve host health, but the mechanisms underlying such beneficial effects are often unclear. Here, the authors show that biofilm formation of the probiotic bacteriumB. subtilis extends the lifespan of its host, the nematode C. elegans, by reducing insulin-like signalling.

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Autores principales:	Verónica Donato, Facundo Rodríguez Ayala, Sebastián Cogliati, Carlos Bauman, Juan Gabriel Costa, Cecilia Leñini, Roberto Grau
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/081e44cf916d495f9d94bc0a10d7f6fd
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id	oai:doaj.org-article:081e44cf916d495f9d94bc0a10d7f6fd
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spelling	oai:doaj.org-article:081e44cf916d495f9d94bc0a10d7f6fd2021-12-02T14:41:20ZBacillus subtilis biofilm extends Caenorhabditis elegans longevity through downregulation of the insulin-like signalling pathway10.1038/ncomms143322041-1723https://doaj.org/article/081e44cf916d495f9d94bc0a10d7f6fd2017-01-01T00:00:00Zhttps://doi.org/10.1038/ncomms14332https://doaj.org/toc/2041-1723Probiotic bacteria can improve host health, but the mechanisms underlying such beneficial effects are often unclear. Here, the authors show that biofilm formation of the probiotic bacteriumB. subtilis extends the lifespan of its host, the nematode C. elegans, by reducing insulin-like signalling.Verónica DonatoFacundo Rodríguez AyalaSebastián CogliatiCarlos BaumanJuan Gabriel CostaCecilia LeñiniRoberto GrauNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Verónica Donato Facundo Rodríguez Ayala Sebastián Cogliati Carlos Bauman Juan Gabriel Costa Cecilia Leñini Roberto Grau Bacillus subtilis biofilm extends Caenorhabditis elegans longevity through downregulation of the insulin-like signalling pathway
description	Probiotic bacteria can improve host health, but the mechanisms underlying such beneficial effects are often unclear. Here, the authors show that biofilm formation of the probiotic bacteriumB. subtilis extends the lifespan of its host, the nematode C. elegans, by reducing insulin-like signalling.
format	article
author	Verónica Donato Facundo Rodríguez Ayala Sebastián Cogliati Carlos Bauman Juan Gabriel Costa Cecilia Leñini Roberto Grau
author_facet	Verónica Donato Facundo Rodríguez Ayala Sebastián Cogliati Carlos Bauman Juan Gabriel Costa Cecilia Leñini Roberto Grau
author_sort	Verónica Donato
title	Bacillus subtilis biofilm extends Caenorhabditis elegans longevity through downregulation of the insulin-like signalling pathway
title_short	Bacillus subtilis biofilm extends Caenorhabditis elegans longevity through downregulation of the insulin-like signalling pathway
title_full	Bacillus subtilis biofilm extends Caenorhabditis elegans longevity through downregulation of the insulin-like signalling pathway
title_fullStr	Bacillus subtilis biofilm extends Caenorhabditis elegans longevity through downregulation of the insulin-like signalling pathway
title_full_unstemmed	Bacillus subtilis biofilm extends Caenorhabditis elegans longevity through downregulation of the insulin-like signalling pathway
title_sort	bacillus subtilis biofilm extends caenorhabditis elegans longevity through downregulation of the insulin-like signalling pathway
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/081e44cf916d495f9d94bc0a10d7f6fd
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Bacillus subtilis biofilm extends Caenorhabditis elegans longevity through downregulation of the insulin-like signalling pathway

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