Electrostatic melting in a single-molecule field-effect transistor with applications in genomic identification
DNA hybridization of two single-strands to form a double-stranded helix is widely used for genomic identification applications. Here, Vernicket al. record duplex formation of 20-mer oligonucleotide using a single-molecule field-effect transistor, where DNA kinetics is affected by electrostatic bias.
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Nature Portfolio
2017
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oai:doaj.org-article:08216ccfafbf4770afb92dd51114dd3a2021-12-02T15:39:03ZElectrostatic melting in a single-molecule field-effect transistor with applications in genomic identification10.1038/ncomms154502041-1723https://doaj.org/article/08216ccfafbf4770afb92dd51114dd3a2017-05-01T00:00:00Zhttps://doi.org/10.1038/ncomms15450https://doaj.org/toc/2041-1723DNA hybridization of two single-strands to form a double-stranded helix is widely used for genomic identification applications. Here, Vernicket al. record duplex formation of 20-mer oligonucleotide using a single-molecule field-effect transistor, where DNA kinetics is affected by electrostatic bias.Sefi VernickScott M. TrocchiaSteven B. WarrenErik F. YoungDelphine BouillyRuben L. GonzalezColin NuckollsKenneth L. ShepardNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-9 (2017) |
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Science Q Sefi Vernick Scott M. Trocchia Steven B. Warren Erik F. Young Delphine Bouilly Ruben L. Gonzalez Colin Nuckolls Kenneth L. Shepard Electrostatic melting in a single-molecule field-effect transistor with applications in genomic identification |
description |
DNA hybridization of two single-strands to form a double-stranded helix is widely used for genomic identification applications. Here, Vernicket al. record duplex formation of 20-mer oligonucleotide using a single-molecule field-effect transistor, where DNA kinetics is affected by electrostatic bias. |
format |
article |
author |
Sefi Vernick Scott M. Trocchia Steven B. Warren Erik F. Young Delphine Bouilly Ruben L. Gonzalez Colin Nuckolls Kenneth L. Shepard |
author_facet |
Sefi Vernick Scott M. Trocchia Steven B. Warren Erik F. Young Delphine Bouilly Ruben L. Gonzalez Colin Nuckolls Kenneth L. Shepard |
author_sort |
Sefi Vernick |
title |
Electrostatic melting in a single-molecule field-effect transistor with applications in genomic identification |
title_short |
Electrostatic melting in a single-molecule field-effect transistor with applications in genomic identification |
title_full |
Electrostatic melting in a single-molecule field-effect transistor with applications in genomic identification |
title_fullStr |
Electrostatic melting in a single-molecule field-effect transistor with applications in genomic identification |
title_full_unstemmed |
Electrostatic melting in a single-molecule field-effect transistor with applications in genomic identification |
title_sort |
electrostatic melting in a single-molecule field-effect transistor with applications in genomic identification |
publisher |
Nature Portfolio |
publishDate |
2017 |
url |
https://doaj.org/article/08216ccfafbf4770afb92dd51114dd3a |
work_keys_str_mv |
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