Electrostatic melting in a single-molecule field-effect transistor with applications in genomic identification

DNA hybridization of two single-strands to form a double-stranded helix is widely used for genomic identification applications. Here, Vernicket al. record duplex formation of 20-mer oligonucleotide using a single-molecule field-effect transistor, where DNA kinetics is affected by electrostatic bias.

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Autores principales: Sefi Vernick, Scott M. Trocchia, Steven B. Warren, Erik F. Young, Delphine Bouilly, Ruben L. Gonzalez, Colin Nuckolls, Kenneth L. Shepard
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/08216ccfafbf4770afb92dd51114dd3a
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spelling oai:doaj.org-article:08216ccfafbf4770afb92dd51114dd3a2021-12-02T15:39:03ZElectrostatic melting in a single-molecule field-effect transistor with applications in genomic identification10.1038/ncomms154502041-1723https://doaj.org/article/08216ccfafbf4770afb92dd51114dd3a2017-05-01T00:00:00Zhttps://doi.org/10.1038/ncomms15450https://doaj.org/toc/2041-1723DNA hybridization of two single-strands to form a double-stranded helix is widely used for genomic identification applications. Here, Vernicket al. record duplex formation of 20-mer oligonucleotide using a single-molecule field-effect transistor, where DNA kinetics is affected by electrostatic bias.Sefi VernickScott M. TrocchiaSteven B. WarrenErik F. YoungDelphine BouillyRuben L. GonzalezColin NuckollsKenneth L. ShepardNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-9 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Sefi Vernick
Scott M. Trocchia
Steven B. Warren
Erik F. Young
Delphine Bouilly
Ruben L. Gonzalez
Colin Nuckolls
Kenneth L. Shepard
Electrostatic melting in a single-molecule field-effect transistor with applications in genomic identification
description DNA hybridization of two single-strands to form a double-stranded helix is widely used for genomic identification applications. Here, Vernicket al. record duplex formation of 20-mer oligonucleotide using a single-molecule field-effect transistor, where DNA kinetics is affected by electrostatic bias.
format article
author Sefi Vernick
Scott M. Trocchia
Steven B. Warren
Erik F. Young
Delphine Bouilly
Ruben L. Gonzalez
Colin Nuckolls
Kenneth L. Shepard
author_facet Sefi Vernick
Scott M. Trocchia
Steven B. Warren
Erik F. Young
Delphine Bouilly
Ruben L. Gonzalez
Colin Nuckolls
Kenneth L. Shepard
author_sort Sefi Vernick
title Electrostatic melting in a single-molecule field-effect transistor with applications in genomic identification
title_short Electrostatic melting in a single-molecule field-effect transistor with applications in genomic identification
title_full Electrostatic melting in a single-molecule field-effect transistor with applications in genomic identification
title_fullStr Electrostatic melting in a single-molecule field-effect transistor with applications in genomic identification
title_full_unstemmed Electrostatic melting in a single-molecule field-effect transistor with applications in genomic identification
title_sort electrostatic melting in a single-molecule field-effect transistor with applications in genomic identification
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/08216ccfafbf4770afb92dd51114dd3a
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