A high-content RNAi screen reveals multiple roles for long noncoding RNAs in cell division

A high-content RNAi screen reveals multiple roles for long noncoding RNAs in cell division

Long noncoding RNAs (lncRNAs) regulate key steps of cell division. Here, the authors perform a comprehensive RNAi imaging screen targeting more than 2,000 human lncRNAs, and suggest a role of chromatin-associated linc00899 in regulation of cell division by suppressing the transcription of microtubul...

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Autores principales: Lovorka Stojic, Aaron T. L. Lun, Patrice Mascalchi, Christina Ernst, Aisling M. Redmond, Jasmin Mangei, Alexis R. Barr, Vicky Bousgouni, Chris Bakal, John C. Marioni, Duncan T. Odom, Fanni Gergely
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Science
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Acceso en línea:https://doaj.org/article/0822bd0027864a7a9eecc223dca2b6f0
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