Non-invasive imaging using reporter genes altering cellular water permeability

Magnetic resonance imaging combined with molecular reporters can visualise cellular functions in intact organisms. Here Mukherjeeet al. present a cellular imaging approach based on intracellular changes in water diffusion using human aquaporin 1 gene as a genetically encoded reporter for MRI.

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Detalles Bibliográficos
Autores principales: Arnab Mukherjee, Di Wu, Hunter C. Davis, Mikhail G. Shapiro
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/082b417eed5047fd965e93f515b1f4ab
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Descripción
Sumario:Magnetic resonance imaging combined with molecular reporters can visualise cellular functions in intact organisms. Here Mukherjeeet al. present a cellular imaging approach based on intracellular changes in water diffusion using human aquaporin 1 gene as a genetically encoded reporter for MRI.