Cardiolipin exposure on the outer mitochondrial membrane modulates α-synuclein

Cardiolipin exposure on the outer mitochondrial membrane modulates α-synuclein

Cardiolipin is a phospholipid component of the inner mitochondrial membrane. Here the authors demonstrate that cardiolipin interacts with mutant α-synuclein, and that impaired cardiolipin function can lead to spread of α-synuclein between neurons.

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Detalles Bibliográficos
Autores principales: Tammy Ryan, Vladimir V. Bamm, Morgan G. Stykel, Carla L. Coackley, Kayla M. Humphries, Rhiannon Jamieson-Williams, Rajesh Ambasudhan, Dick D. Mosser, Stuart A. Lipton, George Harauz, Scott D. Ryan
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/0839cad1dc084b31b2fb1c7ae7cd4162
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