Profiling Atlantic salmon B cell populations: CpG-mediated TLR-ligation enhances IgM secretion and modulates immune gene expression

Abstract While TLR-activated pathways are key regulators of B cell responses in mammals, their impact on teleost B cells are scarcely addressed. Here, the potential of Atlantic salmon B cells to respond to TLR ligands was shown by demonstrating a constitutive expression of nucleic-acid sensing TLRs...

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Autores principales: Shiferaw Jenberie, Hanna L. Thim, J. Oriol Sunyer, Karsten Skjødt, Ingvill Jensen, Jorunn B. Jørgensen
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/083e5688e7144c49802a15f07933a69c
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