Inflammation‐induced left ventricular fibrosis is partially mediated by tumor necrosis factor‐α

Abstract Objective To determine the mechanisms of inflammation‐induced left ventricular (LV) remodeling and effects of blocking circulating tumor necrosis factor alpha (TNF‐α) in a model of systemic inflammation. Methods Seventy Sprague‐Dawley rats were divided into three groups: the control group,...

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Bibliographic Details
Main Authors: Ashmeetha Manilall, Lebogang Mokotedi, Sulè Gunter, Regina Le Roux, Serena Fourie, Colleen A. Flanagan, Aletta M.E. Millen
Format: article
Language:EN
Published: Wiley 2021
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Online Access:https://doaj.org/article/084981e9d39d49d897adb0c6dd483b61
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