Intratibial injection of human multiple myeloma cells in NOD/SCID IL-2Rγ(null) mice mimics human myeloma and serves as a valuable tool for the development of anticancer strategies.

Intratibial injection of human multiple myeloma cells in NOD/SCID IL-2Rγ(null) mice mimics human myeloma and serves as a valuable tool for the development of anticancer strategies.

<h4>Background</h4>We systematically analyzed multiple myeloma (MM) cell lines and patient bone marrow cells for their engraftment capacity in immunodeficient mice and validated the response of the resulting xenografts to antimyeloma agents.<h4>Design and methods</h4>Using fl...

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Autores principales: Julia Schueler, Dagmar Wider, Kerstin Klingner, Gabrielle M Siegers, Annette M May, Ralph Wäsch, Heinz-Herbert Fiebig, Monika Engelhardt
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
Materias:
Medicine
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Science
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Acceso en línea:https://doaj.org/article/084d0622fa22403885cc394eda0e439b
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