IMPACT OF BONE MARROW-DERIVED MULTIPOTENT MESENCHYMAL STROMAL CELLS ON SPEED OF POLYCAPROLACTONE AND POLYHYDROXYALKANOATE SCAFFOLDS BIODEGRADATION

The impact of bone marrow-derived multipotent mesenchymal stromal cells of a bone brain (MSCs BB) on the speed of polycaprolactone and polyhydroxyalkanoate scaffolds biodegradation was studied. The presence of cells on the scaffolds surface was found to catalyze their resorption. 2 months after MSCs...

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Autores principales: L. V. Antonova, A. Y. Burago, V. G. Matveyeva, Y. A. Kudryavtseva, M. V. Nasonova, Y. G. Toropova, E. A. Velikanova, A. S. Golovkin
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Publicado: Scientific Сentre for Family Health and Human Reproduction Problems 2012
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Acceso en línea:https://doaj.org/article/085434c168e547008d35428e8f0b5b22
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spelling oai:doaj.org-article:085434c168e547008d35428e8f0b5b222021-11-23T06:14:19ZIMPACT OF BONE MARROW-DERIVED MULTIPOTENT MESENCHYMAL STROMAL CELLS ON SPEED OF POLYCAPROLACTONE AND POLYHYDROXYALKANOATE SCAFFOLDS BIODEGRADATION2541-94202587-9596https://doaj.org/article/085434c168e547008d35428e8f0b5b222012-05-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/927https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596The impact of bone marrow-derived multipotent mesenchymal stromal cells of a bone brain (MSCs BB) on the speed of polycaprolactone and polyhydroxyalkanoate scaffolds biodegradation was studied. The presence of cells on the scaffolds surface was found to catalyze their resorption. 2 months after MSCs-covered scaffolds had. been subcutaneously implanted in rats they degraded completely while scaffolds, which had no MSCs cover, had partially resorbed by that time. The obtained results make necessary further studying of MSCs impact mechanisms on biopolymers resorption speed.L. V. AntonovaA. Y. BuragoV. G. MatveyevaY. A. KudryavtsevaM. V. NasonovaY. G. ToropovaE. A. VelikanovaA. S. GolovkinScientific Сentre for Family Health and Human Reproduction Problemsarticlemultipotent mesenchymal stromal cellsbiopolymersbiodegradation timeScienceQRUActa Biomedica Scientifica, Vol 0, Iss 3(2), Pp 249-252 (2012)
institution DOAJ
collection DOAJ
language RU
topic multipotent mesenchymal stromal cells
biopolymers
biodegradation time
Science
Q
spellingShingle multipotent mesenchymal stromal cells
biopolymers
biodegradation time
Science
Q
L. V. Antonova
A. Y. Burago
V. G. Matveyeva
Y. A. Kudryavtseva
M. V. Nasonova
Y. G. Toropova
E. A. Velikanova
A. S. Golovkin
IMPACT OF BONE MARROW-DERIVED MULTIPOTENT MESENCHYMAL STROMAL CELLS ON SPEED OF POLYCAPROLACTONE AND POLYHYDROXYALKANOATE SCAFFOLDS BIODEGRADATION
description The impact of bone marrow-derived multipotent mesenchymal stromal cells of a bone brain (MSCs BB) on the speed of polycaprolactone and polyhydroxyalkanoate scaffolds biodegradation was studied. The presence of cells on the scaffolds surface was found to catalyze their resorption. 2 months after MSCs-covered scaffolds had. been subcutaneously implanted in rats they degraded completely while scaffolds, which had no MSCs cover, had partially resorbed by that time. The obtained results make necessary further studying of MSCs impact mechanisms on biopolymers resorption speed.
format article
author L. V. Antonova
A. Y. Burago
V. G. Matveyeva
Y. A. Kudryavtseva
M. V. Nasonova
Y. G. Toropova
E. A. Velikanova
A. S. Golovkin
author_facet L. V. Antonova
A. Y. Burago
V. G. Matveyeva
Y. A. Kudryavtseva
M. V. Nasonova
Y. G. Toropova
E. A. Velikanova
A. S. Golovkin
author_sort L. V. Antonova
title IMPACT OF BONE MARROW-DERIVED MULTIPOTENT MESENCHYMAL STROMAL CELLS ON SPEED OF POLYCAPROLACTONE AND POLYHYDROXYALKANOATE SCAFFOLDS BIODEGRADATION
title_short IMPACT OF BONE MARROW-DERIVED MULTIPOTENT MESENCHYMAL STROMAL CELLS ON SPEED OF POLYCAPROLACTONE AND POLYHYDROXYALKANOATE SCAFFOLDS BIODEGRADATION
title_full IMPACT OF BONE MARROW-DERIVED MULTIPOTENT MESENCHYMAL STROMAL CELLS ON SPEED OF POLYCAPROLACTONE AND POLYHYDROXYALKANOATE SCAFFOLDS BIODEGRADATION
title_fullStr IMPACT OF BONE MARROW-DERIVED MULTIPOTENT MESENCHYMAL STROMAL CELLS ON SPEED OF POLYCAPROLACTONE AND POLYHYDROXYALKANOATE SCAFFOLDS BIODEGRADATION
title_full_unstemmed IMPACT OF BONE MARROW-DERIVED MULTIPOTENT MESENCHYMAL STROMAL CELLS ON SPEED OF POLYCAPROLACTONE AND POLYHYDROXYALKANOATE SCAFFOLDS BIODEGRADATION
title_sort impact of bone marrow-derived multipotent mesenchymal stromal cells on speed of polycaprolactone and polyhydroxyalkanoate scaffolds biodegradation
publisher Scientific Сentre for Family Health and Human Reproduction Problems
publishDate 2012
url https://doaj.org/article/085434c168e547008d35428e8f0b5b22
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