Split-Cre complementation restores combination activity on transgene excision in hair roots of transgenic tobacco.
The Cre/loxP system is increasingly exploited for genetic manipulation of DNA in vitro and in vivo. It was previously reported that inactive ''split-Cre'' fragments could restore Cre activity in transgenic mice when overlapping co-expression was controlled by two different promot...
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Main Authors: | Mengling Wen, Yuan Gao, Lijun Wang, Lingyu Ran, Jiahui Li, Keming Luo |
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Format: | article |
Language: | EN |
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Public Library of Science (PLoS)
2014
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Online Access: | https://doaj.org/article/08565637f9a34f6ab4e416cc01cb6f43 |
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