Split-Cre complementation restores combination activity on transgene excision in hair roots of transgenic tobacco.

The Cre/loxP system is increasingly exploited for genetic manipulation of DNA in vitro and in vivo. It was previously reported that inactive ''split-Cre'' fragments could restore Cre activity in transgenic mice when overlapping co-expression was controlled by two different promot...

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Auteurs principaux: Mengling Wen, Yuan Gao, Lijun Wang, Lingyu Ran, Jiahui Li, Keming Luo
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2014
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Accès en ligne:https://doaj.org/article/08565637f9a34f6ab4e416cc01cb6f43
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