Discovery and enantiocontrol of axially chiral urazoles via organocatalytic tyrosine click reaction

Axially chiral compounds play an important role in areas such as asymmetric catalysis. Here, the authors report an organocatalytic asymmetric tyrosine click-like reaction, giving access to enantio enriched urazoles with restricted rotation around an N-C bond.

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Autores principales: Ji-Wei Zhang, Jin-Hui Xu, Dao-Juan Cheng, Chuan Shi, Xin-Yuan Liu, Bin Tan
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/085c6f5ffdcc43e1b6889cd6bdfd31db
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spelling oai:doaj.org-article:085c6f5ffdcc43e1b6889cd6bdfd31db2021-12-02T17:31:34ZDiscovery and enantiocontrol of axially chiral urazoles via organocatalytic tyrosine click reaction10.1038/ncomms106772041-1723https://doaj.org/article/085c6f5ffdcc43e1b6889cd6bdfd31db2016-02-01T00:00:00Zhttps://doi.org/10.1038/ncomms10677https://doaj.org/toc/2041-1723Axially chiral compounds play an important role in areas such as asymmetric catalysis. Here, the authors report an organocatalytic asymmetric tyrosine click-like reaction, giving access to enantio enriched urazoles with restricted rotation around an N-C bond.Ji-Wei ZhangJin-Hui XuDao-Juan ChengChuan ShiXin-Yuan LiuBin TanNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Ji-Wei Zhang
Jin-Hui Xu
Dao-Juan Cheng
Chuan Shi
Xin-Yuan Liu
Bin Tan
Discovery and enantiocontrol of axially chiral urazoles via organocatalytic tyrosine click reaction
description Axially chiral compounds play an important role in areas such as asymmetric catalysis. Here, the authors report an organocatalytic asymmetric tyrosine click-like reaction, giving access to enantio enriched urazoles with restricted rotation around an N-C bond.
format article
author Ji-Wei Zhang
Jin-Hui Xu
Dao-Juan Cheng
Chuan Shi
Xin-Yuan Liu
Bin Tan
author_facet Ji-Wei Zhang
Jin-Hui Xu
Dao-Juan Cheng
Chuan Shi
Xin-Yuan Liu
Bin Tan
author_sort Ji-Wei Zhang
title Discovery and enantiocontrol of axially chiral urazoles via organocatalytic tyrosine click reaction
title_short Discovery and enantiocontrol of axially chiral urazoles via organocatalytic tyrosine click reaction
title_full Discovery and enantiocontrol of axially chiral urazoles via organocatalytic tyrosine click reaction
title_fullStr Discovery and enantiocontrol of axially chiral urazoles via organocatalytic tyrosine click reaction
title_full_unstemmed Discovery and enantiocontrol of axially chiral urazoles via organocatalytic tyrosine click reaction
title_sort discovery and enantiocontrol of axially chiral urazoles via organocatalytic tyrosine click reaction
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/085c6f5ffdcc43e1b6889cd6bdfd31db
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AT daojuancheng discoveryandenantiocontrolofaxiallychiralurazolesviaorganocatalytictyrosineclickreaction
AT chuanshi discoveryandenantiocontrolofaxiallychiralurazolesviaorganocatalytictyrosineclickreaction
AT xinyuanliu discoveryandenantiocontrolofaxiallychiralurazolesviaorganocatalytictyrosineclickreaction
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