Discovery and enantiocontrol of axially chiral urazoles via organocatalytic tyrosine click reaction
Axially chiral compounds play an important role in areas such as asymmetric catalysis. Here, the authors report an organocatalytic asymmetric tyrosine click-like reaction, giving access to enantio enriched urazoles with restricted rotation around an N-C bond.
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2016
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oai:doaj.org-article:085c6f5ffdcc43e1b6889cd6bdfd31db2021-12-02T17:31:34ZDiscovery and enantiocontrol of axially chiral urazoles via organocatalytic tyrosine click reaction10.1038/ncomms106772041-1723https://doaj.org/article/085c6f5ffdcc43e1b6889cd6bdfd31db2016-02-01T00:00:00Zhttps://doi.org/10.1038/ncomms10677https://doaj.org/toc/2041-1723Axially chiral compounds play an important role in areas such as asymmetric catalysis. Here, the authors report an organocatalytic asymmetric tyrosine click-like reaction, giving access to enantio enriched urazoles with restricted rotation around an N-C bond.Ji-Wei ZhangJin-Hui XuDao-Juan ChengChuan ShiXin-Yuan LiuBin TanNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-10 (2016) |
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Science Q Ji-Wei Zhang Jin-Hui Xu Dao-Juan Cheng Chuan Shi Xin-Yuan Liu Bin Tan Discovery and enantiocontrol of axially chiral urazoles via organocatalytic tyrosine click reaction |
description |
Axially chiral compounds play an important role in areas such as asymmetric catalysis. Here, the authors report an organocatalytic asymmetric tyrosine click-like reaction, giving access to enantio enriched urazoles with restricted rotation around an N-C bond. |
format |
article |
author |
Ji-Wei Zhang Jin-Hui Xu Dao-Juan Cheng Chuan Shi Xin-Yuan Liu Bin Tan |
author_facet |
Ji-Wei Zhang Jin-Hui Xu Dao-Juan Cheng Chuan Shi Xin-Yuan Liu Bin Tan |
author_sort |
Ji-Wei Zhang |
title |
Discovery and enantiocontrol of axially chiral urazoles via organocatalytic tyrosine click reaction |
title_short |
Discovery and enantiocontrol of axially chiral urazoles via organocatalytic tyrosine click reaction |
title_full |
Discovery and enantiocontrol of axially chiral urazoles via organocatalytic tyrosine click reaction |
title_fullStr |
Discovery and enantiocontrol of axially chiral urazoles via organocatalytic tyrosine click reaction |
title_full_unstemmed |
Discovery and enantiocontrol of axially chiral urazoles via organocatalytic tyrosine click reaction |
title_sort |
discovery and enantiocontrol of axially chiral urazoles via organocatalytic tyrosine click reaction |
publisher |
Nature Portfolio |
publishDate |
2016 |
url |
https://doaj.org/article/085c6f5ffdcc43e1b6889cd6bdfd31db |
work_keys_str_mv |
AT jiweizhang discoveryandenantiocontrolofaxiallychiralurazolesviaorganocatalytictyrosineclickreaction AT jinhuixu discoveryandenantiocontrolofaxiallychiralurazolesviaorganocatalytictyrosineclickreaction AT daojuancheng discoveryandenantiocontrolofaxiallychiralurazolesviaorganocatalytictyrosineclickreaction AT chuanshi discoveryandenantiocontrolofaxiallychiralurazolesviaorganocatalytictyrosineclickreaction AT xinyuanliu discoveryandenantiocontrolofaxiallychiralurazolesviaorganocatalytictyrosineclickreaction AT bintan discoveryandenantiocontrolofaxiallychiralurazolesviaorganocatalytictyrosineclickreaction |
_version_ |
1718380533870755840 |