Discovery and enantiocontrol of axially chiral urazoles via organocatalytic tyrosine click reaction

Axially chiral compounds play an important role in areas such as asymmetric catalysis. Here, the authors report an organocatalytic asymmetric tyrosine click-like reaction, giving access to enantio enriched urazoles with restricted rotation around an N-C bond.

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Auteurs principaux: Ji-Wei Zhang, Jin-Hui Xu, Dao-Juan Cheng, Chuan Shi, Xin-Yuan Liu, Bin Tan
Format: article
Langue:EN
Publié: Nature Portfolio 2016
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Q
Accès en ligne:https://doaj.org/article/085c6f5ffdcc43e1b6889cd6bdfd31db
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