Drug delivery approaches for breast cancer

Santosh Kumar Singh,1 Shriti Singh,2 James W Lillard Jr,1 Rajesh Singh1 1Department of Microbiology, Biochemistry and Immunology, Morehouse School of Medicine, Atlanta, GA, USA; 2Department of Kriya Sharir, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India Abstract: Breast c...

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Autores principales:	Singh SK, Singh S, Lillard JW Jr, Singh R
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2017
Materias:	Breast cancer Nanoparticles Drugs delivery systems Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/086d958c4ff04f69b127b5cb0cf495a1
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spelling	oai:doaj.org-article:086d958c4ff04f69b127b5cb0cf495a12021-12-02T03:58:30ZDrug delivery approaches for breast cancer1178-2013https://doaj.org/article/086d958c4ff04f69b127b5cb0cf495a12017-08-01T00:00:00Zhttps://www.dovepress.com/drug-delivery-approaches-for-breast-cancer-peer-reviewed-article-IJNhttps://doaj.org/toc/1178-2013Santosh Kumar Singh,1 Shriti Singh,2 James W Lillard Jr,1 Rajesh Singh1 1Department of Microbiology, Biochemistry and Immunology, Morehouse School of Medicine, Atlanta, GA, USA; 2Department of Kriya Sharir, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India Abstract: Breast cancer is one of the most common cancers affecting women worldwide. The controlled release of drugs to the precise site of the disease using a nanocarrier vehicle increases the therapeutic efficiency of the drugs. Nanotechnology-based approaches used to endorse clinical improvement from a disease also help to understand the interaction of malignant cells with their microenvironment. Receptor-based targeting is another approach for drug delivery which is undergoing clinical trials. Nanoparticles (NPs) delivery has been proven to promise high loading capacity, less toxicity, and stability of the drugs or biomolecules compared to traditional chemotherapeutic drugs. The goal of this review is to present the current problems of breast cancer therapy and discuss the NP-based targeting to overcome the hurdles of conventional drug therapy approach. Keywords: breast cancer, nanoparticles, drug delivery systemsSingh SKSingh SLillard JW JrSingh RDove Medical PressarticleBreast cancerNanoparticlesDrugs delivery systemsMedicine (General)R5-920ENInternational Journal of Nanomedicine, Vol Volume 12, Pp 6205-6218 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Breast cancer Nanoparticles Drugs delivery systems Medicine (General) R5-920
spellingShingle	Breast cancer Nanoparticles Drugs delivery systems Medicine (General) R5-920 Singh SK Singh S Lillard JW Jr Singh R Drug delivery approaches for breast cancer
description	Santosh Kumar Singh,1 Shriti Singh,2 James W Lillard Jr,1 Rajesh Singh1 1Department of Microbiology, Biochemistry and Immunology, Morehouse School of Medicine, Atlanta, GA, USA; 2Department of Kriya Sharir, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India Abstract: Breast cancer is one of the most common cancers affecting women worldwide. The controlled release of drugs to the precise site of the disease using a nanocarrier vehicle increases the therapeutic efficiency of the drugs. Nanotechnology-based approaches used to endorse clinical improvement from a disease also help to understand the interaction of malignant cells with their microenvironment. Receptor-based targeting is another approach for drug delivery which is undergoing clinical trials. Nanoparticles (NPs) delivery has been proven to promise high loading capacity, less toxicity, and stability of the drugs or biomolecules compared to traditional chemotherapeutic drugs. The goal of this review is to present the current problems of breast cancer therapy and discuss the NP-based targeting to overcome the hurdles of conventional drug therapy approach. Keywords: breast cancer, nanoparticles, drug delivery systems
format	article
author	Singh SK Singh S Lillard JW Jr Singh R
author_facet	Singh SK Singh S Lillard JW Jr Singh R
author_sort	Singh SK
title	Drug delivery approaches for breast cancer
title_short	Drug delivery approaches for breast cancer
title_full	Drug delivery approaches for breast cancer
title_fullStr	Drug delivery approaches for breast cancer
title_full_unstemmed	Drug delivery approaches for breast cancer
title_sort	drug delivery approaches for breast cancer
publisher	Dove Medical Press
publishDate	2017
url	https://doaj.org/article/086d958c4ff04f69b127b5cb0cf495a1
work_keys_str_mv	AT singhsk drugdeliveryapproachesforbreastcancer AT singhs drugdeliveryapproachesforbreastcancer AT lillardjwjr drugdeliveryapproachesforbreastcancer AT singhr drugdeliveryapproachesforbreastcancer
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Drug delivery approaches for breast cancer

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