Recurrent network dynamics shape direction selectivity in primary auditory cortex

Aponte et al. show that cortical direction selectivity to frequency modulated sounds is shaped by asymmetric signal amplification within recurrent circuits. Optogenetics and network modelling demonstrate that this asymmetry arises due to broad spatial topography of SOM cell mediated inhibition.

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Detalles Bibliográficos
Autores principales: Destinee A. Aponte, Gregory Handy, Amber M. Kline, Hiroaki Tsukano, Brent Doiron, Hiroyuki K. Kato
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/0872fd73af1640909e596661814b3190
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Descripción
Sumario:Aponte et al. show that cortical direction selectivity to frequency modulated sounds is shaped by asymmetric signal amplification within recurrent circuits. Optogenetics and network modelling demonstrate that this asymmetry arises due to broad spatial topography of SOM cell mediated inhibition.