The Trypanosome UDP-Glucose Pyrophosphorylase Is Imported by Piggybacking into Glycosomes, Where Unconventional Sugar Nucleotide Synthesis Takes Place

Unusual compartmentalization of metabolic pathways within organelles is one of the most enigmatic features of trypanosomatids. These unicellular eukaryotes are the only organisms that sequestered glycolysis inside peroxisomes (glycosomes), although the selective advantage of this compartmentalizati...

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Autores principales: Oriana Villafraz, Hélène Baudouin, Muriel Mazet, Hanna Kulyk, Jean-William Dupuy, Erika Pineda, Cyrille Botté, Daniel Ken Inaoka, Jean-Charles Portais, Frédéric Bringaud
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Publicado: American Society for Microbiology 2021
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Acceso en línea:https://doaj.org/article/087ef0462d394133934b9d2367a4afc4
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spelling oai:doaj.org-article:087ef0462d394133934b9d2367a4afc42021-11-03T21:15:03ZThe Trypanosome UDP-Glucose Pyrophosphorylase Is Imported by Piggybacking into Glycosomes, Where Unconventional Sugar Nucleotide Synthesis Takes Place2150-751110.1128/mBio.00375-21https://doaj.org/article/087ef0462d394133934b9d2367a4afc42021-06-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mBio.00375-21https://doaj.org/toc/2150-7511 Unusual compartmentalization of metabolic pathways within organelles is one of the most enigmatic features of trypanosomatids. These unicellular eukaryotes are the only organisms that sequestered glycolysis inside peroxisomes (glycosomes), although the selective advantage of this compartmentalization is still not clear.Oriana VillafrazHélène BaudouinMuriel MazetHanna KulykJean-William DupuyErika PinedaCyrille BottéDaniel Ken InaokaJean-Charles PortaisFrédéric BringaudAmerican Society for MicrobiologyarticleMicrobiologyQR1-502ENmBio, Vol 12, Iss 3 (2021)
institution DOAJ
collection DOAJ
language EN
topic Microbiology
QR1-502
spellingShingle Microbiology
QR1-502
Oriana Villafraz
Hélène Baudouin
Muriel Mazet
Hanna Kulyk
Jean-William Dupuy
Erika Pineda
Cyrille Botté
Daniel Ken Inaoka
Jean-Charles Portais
Frédéric Bringaud
The Trypanosome UDP-Glucose Pyrophosphorylase Is Imported by Piggybacking into Glycosomes, Where Unconventional Sugar Nucleotide Synthesis Takes Place
description Unusual compartmentalization of metabolic pathways within organelles is one of the most enigmatic features of trypanosomatids. These unicellular eukaryotes are the only organisms that sequestered glycolysis inside peroxisomes (glycosomes), although the selective advantage of this compartmentalization is still not clear.
format article
author Oriana Villafraz
Hélène Baudouin
Muriel Mazet
Hanna Kulyk
Jean-William Dupuy
Erika Pineda
Cyrille Botté
Daniel Ken Inaoka
Jean-Charles Portais
Frédéric Bringaud
author_facet Oriana Villafraz
Hélène Baudouin
Muriel Mazet
Hanna Kulyk
Jean-William Dupuy
Erika Pineda
Cyrille Botté
Daniel Ken Inaoka
Jean-Charles Portais
Frédéric Bringaud
author_sort Oriana Villafraz
title The Trypanosome UDP-Glucose Pyrophosphorylase Is Imported by Piggybacking into Glycosomes, Where Unconventional Sugar Nucleotide Synthesis Takes Place
title_short The Trypanosome UDP-Glucose Pyrophosphorylase Is Imported by Piggybacking into Glycosomes, Where Unconventional Sugar Nucleotide Synthesis Takes Place
title_full The Trypanosome UDP-Glucose Pyrophosphorylase Is Imported by Piggybacking into Glycosomes, Where Unconventional Sugar Nucleotide Synthesis Takes Place
title_fullStr The Trypanosome UDP-Glucose Pyrophosphorylase Is Imported by Piggybacking into Glycosomes, Where Unconventional Sugar Nucleotide Synthesis Takes Place
title_full_unstemmed The Trypanosome UDP-Glucose Pyrophosphorylase Is Imported by Piggybacking into Glycosomes, Where Unconventional Sugar Nucleotide Synthesis Takes Place
title_sort trypanosome udp-glucose pyrophosphorylase is imported by piggybacking into glycosomes, where unconventional sugar nucleotide synthesis takes place
publisher American Society for Microbiology
publishDate 2021
url https://doaj.org/article/087ef0462d394133934b9d2367a4afc4
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