Toxic element contamination of natural health products and pharmaceutical preparations.

<h4>Background</h4>Concern has recently emerged regarding the safety of natural health products (NHPs)-therapies that are increasingly recommended by various health providers, including conventional physicians. Recognizing that most individuals in the Western world now consume vitamins a...

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Autores principales:	Stephen J Genuis, Gerry Schwalfenberg, Anna-Kristen J Siy, Ilya Rodushkin
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2012
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/08803413344b44ccaad53174a90100d1
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spelling	oai:doaj.org-article:08803413344b44ccaad53174a90100d12021-11-18T08:07:56ZToxic element contamination of natural health products and pharmaceutical preparations.1932-620310.1371/journal.pone.0049676https://doaj.org/article/08803413344b44ccaad53174a90100d12012-01-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23185404/?tool=EBIhttps://doaj.org/toc/1932-6203<h4>Background</h4>Concern has recently emerged regarding the safety of natural health products (NHPs)-therapies that are increasingly recommended by various health providers, including conventional physicians. Recognizing that most individuals in the Western world now consume vitamins and many take herbal agents, this study endeavored to determine levels of toxic element contamination within a range of NHPs.<h4>Methods</h4>Toxic element testing was performed on 121 NHPs (including Ayurvedic, traditional Chinese, and various marine-source products) as well as 49 routinely prescribed pharmaceutical preparations. Testing was also performed on several batches of one prenatal supplement, with multiple samples tested within each batch. Results were compared to existing toxicant regulatory limits.<h4>Results</h4>Toxic element contamination was found in many supplements and pharmaceuticals; levels exceeding established limits were only found in a small percentage of the NHPs tested and none of the drugs tested. Some NHPs demonstrated contamination levels above preferred daily endpoints for mercury, cadmium, lead, arsenic or aluminum. NHPs manufactured in China generally had higher levels of mercury and aluminum.<h4>Conclusions</h4>Exposure to toxic elements is occurring regularly as a result of some contaminated NHPs. Best practices for quality control-developed and implemented by the NHP industry with government oversight-is recommended to guard the safety of unsuspecting consumers.Stephen J GenuisGerry SchwalfenbergAnna-Kristen J SiyIlya RodushkinPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 7, Iss 11, p e49676 (2012)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Stephen J Genuis Gerry Schwalfenberg Anna-Kristen J Siy Ilya Rodushkin Toxic element contamination of natural health products and pharmaceutical preparations.
description	<h4>Background</h4>Concern has recently emerged regarding the safety of natural health products (NHPs)-therapies that are increasingly recommended by various health providers, including conventional physicians. Recognizing that most individuals in the Western world now consume vitamins and many take herbal agents, this study endeavored to determine levels of toxic element contamination within a range of NHPs.<h4>Methods</h4>Toxic element testing was performed on 121 NHPs (including Ayurvedic, traditional Chinese, and various marine-source products) as well as 49 routinely prescribed pharmaceutical preparations. Testing was also performed on several batches of one prenatal supplement, with multiple samples tested within each batch. Results were compared to existing toxicant regulatory limits.<h4>Results</h4>Toxic element contamination was found in many supplements and pharmaceuticals; levels exceeding established limits were only found in a small percentage of the NHPs tested and none of the drugs tested. Some NHPs demonstrated contamination levels above preferred daily endpoints for mercury, cadmium, lead, arsenic or aluminum. NHPs manufactured in China generally had higher levels of mercury and aluminum.<h4>Conclusions</h4>Exposure to toxic elements is occurring regularly as a result of some contaminated NHPs. Best practices for quality control-developed and implemented by the NHP industry with government oversight-is recommended to guard the safety of unsuspecting consumers.
format	article
author	Stephen J Genuis Gerry Schwalfenberg Anna-Kristen J Siy Ilya Rodushkin
author_facet	Stephen J Genuis Gerry Schwalfenberg Anna-Kristen J Siy Ilya Rodushkin
author_sort	Stephen J Genuis
title	Toxic element contamination of natural health products and pharmaceutical preparations.
title_short	Toxic element contamination of natural health products and pharmaceutical preparations.
title_full	Toxic element contamination of natural health products and pharmaceutical preparations.
title_fullStr	Toxic element contamination of natural health products and pharmaceutical preparations.
title_full_unstemmed	Toxic element contamination of natural health products and pharmaceutical preparations.
title_sort	toxic element contamination of natural health products and pharmaceutical preparations.
publisher	Public Library of Science (PLoS)
publishDate	2012
url	https://doaj.org/article/08803413344b44ccaad53174a90100d1
work_keys_str_mv	AT stephenjgenuis toxicelementcontaminationofnaturalhealthproductsandpharmaceuticalpreparations AT gerryschwalfenberg toxicelementcontaminationofnaturalhealthproductsandpharmaceuticalpreparations AT annakristenjsiy toxicelementcontaminationofnaturalhealthproductsandpharmaceuticalpreparations AT ilyarodushkin toxicelementcontaminationofnaturalhealthproductsandpharmaceuticalpreparations
_version_	1718422149446762496

Toxic element contamination of natural health products and pharmaceutical preparations.

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