Chiral acid-catalysed enantioselective C−H functionalization of toluene and its derivatives driven by visible light

Asymmetric transformations involving abundant chemical feedstocks such as toluene and its derivatives are rather rare. Here, the authors report the radical enantioselective C(sp3) −C(sp3) coupling of activated ketones with toluenes by means of chiral acid catalysis to afford enantioenriched tertiary...

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Auteurs principaux:	Fuyuan Li, Dong Tian, Yifan Fan, Richmond Lee, Gang Lu, Yanli Yin, Baokun Qiao, Xiaowei Zhao, Ziwei Xiao, Zhiyong Jiang
Format:	article
Langue:	EN
Publié:	Nature Portfolio 2019
Sujets:	Science Q
Accès en ligne:	https://doaj.org/article/0889e0279be74a959e50bb13a8b17b62
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spelling	oai:doaj.org-article:0889e0279be74a959e50bb13a8b17b622021-12-02T14:38:39ZChiral acid-catalysed enantioselective C−H functionalization of toluene and its derivatives driven by visible light10.1038/s41467-019-09857-92041-1723https://doaj.org/article/0889e0279be74a959e50bb13a8b17b622019-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-09857-9https://doaj.org/toc/2041-1723Asymmetric transformations involving abundant chemical feedstocks such as toluene and its derivatives are rather rare. Here, the authors report the radical enantioselective C(sp3) −C(sp3) coupling of activated ketones with toluenes by means of chiral acid catalysis to afford enantioenriched tertiary alcohols.Fuyuan LiDong TianYifan FanRichmond LeeGang LuYanli YinBaokun QiaoXiaowei ZhaoZiwei XiaoZhiyong JiangNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Fuyuan Li Dong Tian Yifan Fan Richmond Lee Gang Lu Yanli Yin Baokun Qiao Xiaowei Zhao Ziwei Xiao Zhiyong Jiang Chiral acid-catalysed enantioselective C−H functionalization of toluene and its derivatives driven by visible light
description	Asymmetric transformations involving abundant chemical feedstocks such as toluene and its derivatives are rather rare. Here, the authors report the radical enantioselective C(sp3) −C(sp3) coupling of activated ketones with toluenes by means of chiral acid catalysis to afford enantioenriched tertiary alcohols.
format	article
author	Fuyuan Li Dong Tian Yifan Fan Richmond Lee Gang Lu Yanli Yin Baokun Qiao Xiaowei Zhao Ziwei Xiao Zhiyong Jiang
author_facet	Fuyuan Li Dong Tian Yifan Fan Richmond Lee Gang Lu Yanli Yin Baokun Qiao Xiaowei Zhao Ziwei Xiao Zhiyong Jiang
author_sort	Fuyuan Li
title	Chiral acid-catalysed enantioselective C−H functionalization of toluene and its derivatives driven by visible light
title_short	Chiral acid-catalysed enantioselective C−H functionalization of toluene and its derivatives driven by visible light
title_full	Chiral acid-catalysed enantioselective C−H functionalization of toluene and its derivatives driven by visible light
title_fullStr	Chiral acid-catalysed enantioselective C−H functionalization of toluene and its derivatives driven by visible light
title_full_unstemmed	Chiral acid-catalysed enantioselective C−H functionalization of toluene and its derivatives driven by visible light
title_sort	chiral acid-catalysed enantioselective c−h functionalization of toluene and its derivatives driven by visible light
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/0889e0279be74a959e50bb13a8b17b62
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Chiral acid-catalysed enantioselective C−H functionalization of toluene and its derivatives driven by visible light

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