Control of bleeding in surgical procedures: critical appraisal of HEMOPATCH (Sealing Hemostat)

Kevin Michael Lewis,1 Carl Erik Kuntze,2 Heinz Gulle3 1Preclinical Safety and Efficacy, Baxter Healthcare Corporation, Deerfield, IL, USA; 2Medical Affairs, Baxter Healthcare SA, Zurich, Switzerland; 3Surgical Sciences and Engineering, Baxter Medical Products GmbH, Vienna, Austria Abstract: The nee...

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Autores principales:	Lewis KM, Kuntze CE, Gulle H
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2015
Materias:	HEMOPATCH Hemostasis Surgical Hemostasis Sealing Surgical Sealant Medical technology R855-855.5
Acceso en línea:	https://doaj.org/article/088db5d4f8da4020a34c61b5bcd298a2
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spelling	oai:doaj.org-article:088db5d4f8da4020a34c61b5bcd298a22021-12-02T01:50:07ZControl of bleeding in surgical procedures: critical appraisal of HEMOPATCH (Sealing Hemostat)1179-1470https://doaj.org/article/088db5d4f8da4020a34c61b5bcd298a22015-12-01T00:00:00Zhttps://www.dovepress.com/control-of-bleeding-in-surgical-procedures-critical-appraisal-of-hemop-peer-reviewed-article-MDERhttps://doaj.org/toc/1179-1470Kevin Michael Lewis,1 Carl Erik Kuntze,2 Heinz Gulle3 1Preclinical Safety and Efficacy, Baxter Healthcare Corporation, Deerfield, IL, USA; 2Medical Affairs, Baxter Healthcare SA, Zurich, Switzerland; 3Surgical Sciences and Engineering, Baxter Medical Products GmbH, Vienna, Austria Abstract: The need for advanced hemostatic agents increases with the complexity of surgical procedures and use of anticoagulation and antiplatelet treatments. HEMOPATCH (Sealing Hemostat) is a novel, advanced hemostatic pad that is composed of a synthetic, protein-reactive monomer and a collagen backing. The active side is covered with a protein-reactive monomer: N-hydroxysuccinimide functionalized polyethylene glycol (NHS-PEG). NHS-PEG rapidly affixes the collagen pad to tissue to promote and maintain hemostasis. The combined action of the NHS-PEG and collagen is demonstrated to have benefit relative to other hemostatic agents in surgery and preclinical surgical models. This paper reviews the published investigations and case reports of the hemostatic efficacy of HEMOPATCH, wherein HEMOPATCH is demonstrated to be an effective, easy-to-use hemostatic agent in open and minimally invasive surgery of patients with thrombin- or platelet-induced coagulopathies. Keywords: HEMOPATCH, hemostasis, surgical hemostasis, sealing, surgical sealantLewis KMKuntze CEGulle HDove Medical PressarticleHEMOPATCHHemostasisSurgical HemostasisSealingSurgical SealantMedical technologyR855-855.5ENMedical Devices: Evidence and Research, Vol 2016, Iss Issue 1, Pp 1-10 (2015)
institution	DOAJ
collection	DOAJ
language	EN
topic	HEMOPATCH Hemostasis Surgical Hemostasis Sealing Surgical Sealant Medical technology R855-855.5
spellingShingle	HEMOPATCH Hemostasis Surgical Hemostasis Sealing Surgical Sealant Medical technology R855-855.5 Lewis KM Kuntze CE Gulle H Control of bleeding in surgical procedures: critical appraisal of HEMOPATCH (Sealing Hemostat)
description	Kevin Michael Lewis,1 Carl Erik Kuntze,2 Heinz Gulle3 1Preclinical Safety and Efficacy, Baxter Healthcare Corporation, Deerfield, IL, USA; 2Medical Affairs, Baxter Healthcare SA, Zurich, Switzerland; 3Surgical Sciences and Engineering, Baxter Medical Products GmbH, Vienna, Austria Abstract: The need for advanced hemostatic agents increases with the complexity of surgical procedures and use of anticoagulation and antiplatelet treatments. HEMOPATCH (Sealing Hemostat) is a novel, advanced hemostatic pad that is composed of a synthetic, protein-reactive monomer and a collagen backing. The active side is covered with a protein-reactive monomer: N-hydroxysuccinimide functionalized polyethylene glycol (NHS-PEG). NHS-PEG rapidly affixes the collagen pad to tissue to promote and maintain hemostasis. The combined action of the NHS-PEG and collagen is demonstrated to have benefit relative to other hemostatic agents in surgery and preclinical surgical models. This paper reviews the published investigations and case reports of the hemostatic efficacy of HEMOPATCH, wherein HEMOPATCH is demonstrated to be an effective, easy-to-use hemostatic agent in open and minimally invasive surgery of patients with thrombin- or platelet-induced coagulopathies. Keywords: HEMOPATCH, hemostasis, surgical hemostasis, sealing, surgical sealant
format	article
author	Lewis KM Kuntze CE Gulle H
author_facet	Lewis KM Kuntze CE Gulle H
author_sort	Lewis KM
title	Control of bleeding in surgical procedures: critical appraisal of HEMOPATCH (Sealing Hemostat)
title_short	Control of bleeding in surgical procedures: critical appraisal of HEMOPATCH (Sealing Hemostat)
title_full	Control of bleeding in surgical procedures: critical appraisal of HEMOPATCH (Sealing Hemostat)
title_fullStr	Control of bleeding in surgical procedures: critical appraisal of HEMOPATCH (Sealing Hemostat)
title_full_unstemmed	Control of bleeding in surgical procedures: critical appraisal of HEMOPATCH (Sealing Hemostat)
title_sort	control of bleeding in surgical procedures: critical appraisal of hemopatch (sealing hemostat)
publisher	Dove Medical Press
publishDate	2015
url	https://doaj.org/article/088db5d4f8da4020a34c61b5bcd298a2
work_keys_str_mv	AT lewiskm controlofbleedinginsurgicalprocedurescriticalappraisalofhemopatchsealinghemostat AT kuntzece controlofbleedinginsurgicalprocedurescriticalappraisalofhemopatchsealinghemostat AT gulleh controlofbleedinginsurgicalprocedurescriticalappraisalofhemopatchsealinghemostat
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Control of bleeding in surgical procedures: critical appraisal of HEMOPATCH (Sealing Hemostat)

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