Synthesis of difluoromethylated allenes through trifunctionalization of 1,3-enynes

Fluorinated or fluoroalkylated allenes are versatile building blocks for medicinal and material chemistry. Here, the authors show a regioselective trifunctionalization of 1,3-enynes proceeding through double C-F bond formation and concomitant installation of a -NSO2Ph group to the allene moiety.

Guardado en:
Detalles Bibliográficos
Autores principales: Munira Taj Muhammad, Yihang Jiao, Changqing Ye, Mong-Feng Chiou, Muhammad Israr, Xiaotao Zhu, Yajun Li, Zhenhai Wen, Armido Studer, Hongli Bao
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
Materias:
Q
Acceso en línea:https://doaj.org/article/088ff620e653493a9b6d0f5ab973aca1
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:088ff620e653493a9b6d0f5ab973aca1
record_format dspace
spelling oai:doaj.org-article:088ff620e653493a9b6d0f5ab973aca12021-12-02T15:37:19ZSynthesis of difluoromethylated allenes through trifunctionalization of 1,3-enynes10.1038/s41467-019-14254-32041-1723https://doaj.org/article/088ff620e653493a9b6d0f5ab973aca12020-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-14254-3https://doaj.org/toc/2041-1723Fluorinated or fluoroalkylated allenes are versatile building blocks for medicinal and material chemistry. Here, the authors show a regioselective trifunctionalization of 1,3-enynes proceeding through double C-F bond formation and concomitant installation of a -NSO2Ph group to the allene moiety.Munira Taj MuhammadYihang JiaoChangqing YeMong-Feng ChiouMuhammad IsrarXiaotao ZhuYajun LiZhenhai WenArmido StuderHongli BaoNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-8 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Munira Taj Muhammad
Yihang Jiao
Changqing Ye
Mong-Feng Chiou
Muhammad Israr
Xiaotao Zhu
Yajun Li
Zhenhai Wen
Armido Studer
Hongli Bao
Synthesis of difluoromethylated allenes through trifunctionalization of 1,3-enynes
description Fluorinated or fluoroalkylated allenes are versatile building blocks for medicinal and material chemistry. Here, the authors show a regioselective trifunctionalization of 1,3-enynes proceeding through double C-F bond formation and concomitant installation of a -NSO2Ph group to the allene moiety.
format article
author Munira Taj Muhammad
Yihang Jiao
Changqing Ye
Mong-Feng Chiou
Muhammad Israr
Xiaotao Zhu
Yajun Li
Zhenhai Wen
Armido Studer
Hongli Bao
author_facet Munira Taj Muhammad
Yihang Jiao
Changqing Ye
Mong-Feng Chiou
Muhammad Israr
Xiaotao Zhu
Yajun Li
Zhenhai Wen
Armido Studer
Hongli Bao
author_sort Munira Taj Muhammad
title Synthesis of difluoromethylated allenes through trifunctionalization of 1,3-enynes
title_short Synthesis of difluoromethylated allenes through trifunctionalization of 1,3-enynes
title_full Synthesis of difluoromethylated allenes through trifunctionalization of 1,3-enynes
title_fullStr Synthesis of difluoromethylated allenes through trifunctionalization of 1,3-enynes
title_full_unstemmed Synthesis of difluoromethylated allenes through trifunctionalization of 1,3-enynes
title_sort synthesis of difluoromethylated allenes through trifunctionalization of 1,3-enynes
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/088ff620e653493a9b6d0f5ab973aca1
work_keys_str_mv AT muniratajmuhammad synthesisofdifluoromethylatedallenesthroughtrifunctionalizationof13enynes
AT yihangjiao synthesisofdifluoromethylatedallenesthroughtrifunctionalizationof13enynes
AT changqingye synthesisofdifluoromethylatedallenesthroughtrifunctionalizationof13enynes
AT mongfengchiou synthesisofdifluoromethylatedallenesthroughtrifunctionalizationof13enynes
AT muhammadisrar synthesisofdifluoromethylatedallenesthroughtrifunctionalizationof13enynes
AT xiaotaozhu synthesisofdifluoromethylatedallenesthroughtrifunctionalizationof13enynes
AT yajunli synthesisofdifluoromethylatedallenesthroughtrifunctionalizationof13enynes
AT zhenhaiwen synthesisofdifluoromethylatedallenesthroughtrifunctionalizationof13enynes
AT armidostuder synthesisofdifluoromethylatedallenesthroughtrifunctionalizationof13enynes
AT honglibao synthesisofdifluoromethylatedallenesthroughtrifunctionalizationof13enynes
_version_ 1718386213065326592