Synthesis of difluoromethylated allenes through trifunctionalization of 1,3-enynes
Fluorinated or fluoroalkylated allenes are versatile building blocks for medicinal and material chemistry. Here, the authors show a regioselective trifunctionalization of 1,3-enynes proceeding through double C-F bond formation and concomitant installation of a -NSO2Ph group to the allene moiety.
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Nature Portfolio
2020
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oai:doaj.org-article:088ff620e653493a9b6d0f5ab973aca12021-12-02T15:37:19ZSynthesis of difluoromethylated allenes through trifunctionalization of 1,3-enynes10.1038/s41467-019-14254-32041-1723https://doaj.org/article/088ff620e653493a9b6d0f5ab973aca12020-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-14254-3https://doaj.org/toc/2041-1723Fluorinated or fluoroalkylated allenes are versatile building blocks for medicinal and material chemistry. Here, the authors show a regioselective trifunctionalization of 1,3-enynes proceeding through double C-F bond formation and concomitant installation of a -NSO2Ph group to the allene moiety.Munira Taj MuhammadYihang JiaoChangqing YeMong-Feng ChiouMuhammad IsrarXiaotao ZhuYajun LiZhenhai WenArmido StuderHongli BaoNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-8 (2020) |
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Science Q Munira Taj Muhammad Yihang Jiao Changqing Ye Mong-Feng Chiou Muhammad Israr Xiaotao Zhu Yajun Li Zhenhai Wen Armido Studer Hongli Bao Synthesis of difluoromethylated allenes through trifunctionalization of 1,3-enynes |
description |
Fluorinated or fluoroalkylated allenes are versatile building blocks for medicinal and material chemistry. Here, the authors show a regioselective trifunctionalization of 1,3-enynes proceeding through double C-F bond formation and concomitant installation of a -NSO2Ph group to the allene moiety. |
format |
article |
author |
Munira Taj Muhammad Yihang Jiao Changqing Ye Mong-Feng Chiou Muhammad Israr Xiaotao Zhu Yajun Li Zhenhai Wen Armido Studer Hongli Bao |
author_facet |
Munira Taj Muhammad Yihang Jiao Changqing Ye Mong-Feng Chiou Muhammad Israr Xiaotao Zhu Yajun Li Zhenhai Wen Armido Studer Hongli Bao |
author_sort |
Munira Taj Muhammad |
title |
Synthesis of difluoromethylated allenes through trifunctionalization of 1,3-enynes |
title_short |
Synthesis of difluoromethylated allenes through trifunctionalization of 1,3-enynes |
title_full |
Synthesis of difluoromethylated allenes through trifunctionalization of 1,3-enynes |
title_fullStr |
Synthesis of difluoromethylated allenes through trifunctionalization of 1,3-enynes |
title_full_unstemmed |
Synthesis of difluoromethylated allenes through trifunctionalization of 1,3-enynes |
title_sort |
synthesis of difluoromethylated allenes through trifunctionalization of 1,3-enynes |
publisher |
Nature Portfolio |
publishDate |
2020 |
url |
https://doaj.org/article/088ff620e653493a9b6d0f5ab973aca1 |
work_keys_str_mv |
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1718386213065326592 |