HEB is required for the specification of fetal IL-17-producing γδ T cells

HEB is required for the specification of fetal IL-17-producing γδ T cells

The γδ T cell pool includes abundant IL-17-producing cells that protect mucosal surfaces, but the signals that control γδ T cell specification are unclear. Here the authors identify a role for the transcription factor HEB, and antagonistic activity of Id3, in the development of these cells.

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Detalles Bibliográficos
Autores principales: Tracy S. H. In, Ashton Trotman-Grant, Shawn Fahl, Edward L. Y. Chen, Payam Zarin, Amanda J. Moore, David L. Wiest, Juan Carlos Zúñiga-Pflücker, Michele K. Anderson
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Science
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Acceso en línea:https://doaj.org/article/0891f0415e62442cafff5d926ff15f1e
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