Comparison of Equilibrium Deficits in Idiopathic Parkinson’s Disease with Normal Subjects Using Videonystagmography

BACKGROUND AND OBJECTIVE: Parkinson is the most prevalent degenerative disorder of central nervous system. In this disorder other than muscular deficits, oculomotor abnormalities are seen. This is the consequence of basal ganglia impairment. The most common abnormalities include increased saccade la...

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Autores principales:	R Hosseinabadi, AR Sheibanizadeh, GH.A shahidi, A gholampor, M Shahidi
Formato:	article
Lenguaje:	EN FA
Publicado:	Babol University of Medical Sciences 2009
Materias:	oculomotor saccade basal ganglia disorders parkinson Medicine R Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/0894fba80a8541efb741e9fb90f457ba
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spelling	oai:doaj.org-article:0894fba80a8541efb741e9fb90f457ba2021-11-10T09:02:35ZComparison of Equilibrium Deficits in Idiopathic Parkinson’s Disease with Normal Subjects Using Videonystagmography1561-41072251-7170https://doaj.org/article/0894fba80a8541efb741e9fb90f457ba2009-04-01T00:00:00Zhttp://jbums.org/article-1-3149-en.htmlhttps://doaj.org/toc/1561-4107https://doaj.org/toc/2251-7170BACKGROUND AND OBJECTIVE: Parkinson is the most prevalent degenerative disorder of central nervous system. In this disorder other than muscular deficits, oculomotor abnormalities are seen. This is the consequence of basal ganglia impairment. The most common abnormalities include increased saccade latency, hypometric saccades and decreased saccade velocity. The purpose of this study was to compare saccadic parameters using videonystagmography in patients with idiopathic Parkinson’s disease and normal subjects.METHODS: In this cross sectional study, saccadic movements were investigated in 30 patients with idiopathic Parkinson’s disease and 30 normal subjects (35-70 years). Saccade latency, velocity and accuracy were quantitatively analyzed. Saccadic measurements were conducted using videonystagmography.FINDINGS: Parkinsonian group included 18 males and 12 females. Normal group included 20 males and 10 females. Average of horizontal saccadic latency in Parkinsonian patients was 0.4±0.2 and in normal group was 0.3±0.1 that was statistically significant (p<0.001). Accuracy of horizontal saccade in Parkinsonian patients was 36.7% and in normal group was 96.7 % (p<0.001). Velocity of horizontal saccade in Parkinsonian patients was 350.5±85.30 and in normal group was 493.3±79.9 (p<0.001). Differences in right eye was statistically significant (p<0.001).CONCLUSION: This study showed that patients with Parkinson’s disease manifest saccadic deficits. This suggests dopaminergic control of these ocular movements. We can consider these differences as the characteristic of Parkinson disorder in diagnosis and treatment.R Hosseinabadi,AR SheibanizadehGH.A shahidiA gholamporM ShahidiBabol University of Medical Sciencesarticleoculomotorsaccadebasal ganglia disordersparkinsonMedicineRMedicine (General)R5-920ENFAMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, Vol 11, Iss 1, Pp 36-40 (2009)
institution	DOAJ
collection	DOAJ
language	EN FA
topic	oculomotor saccade basal ganglia disorders parkinson Medicine R Medicine (General) R5-920
spellingShingle	oculomotor saccade basal ganglia disorders parkinson Medicine R Medicine (General) R5-920 R Hosseinabadi, AR Sheibanizadeh GH.A shahidi A gholampor M Shahidi Comparison of Equilibrium Deficits in Idiopathic Parkinson’s Disease with Normal Subjects Using Videonystagmography
description	BACKGROUND AND OBJECTIVE: Parkinson is the most prevalent degenerative disorder of central nervous system. In this disorder other than muscular deficits, oculomotor abnormalities are seen. This is the consequence of basal ganglia impairment. The most common abnormalities include increased saccade latency, hypometric saccades and decreased saccade velocity. The purpose of this study was to compare saccadic parameters using videonystagmography in patients with idiopathic Parkinson’s disease and normal subjects.METHODS: In this cross sectional study, saccadic movements were investigated in 30 patients with idiopathic Parkinson’s disease and 30 normal subjects (35-70 years). Saccade latency, velocity and accuracy were quantitatively analyzed. Saccadic measurements were conducted using videonystagmography.FINDINGS: Parkinsonian group included 18 males and 12 females. Normal group included 20 males and 10 females. Average of horizontal saccadic latency in Parkinsonian patients was 0.4±0.2 and in normal group was 0.3±0.1 that was statistically significant (p<0.001). Accuracy of horizontal saccade in Parkinsonian patients was 36.7% and in normal group was 96.7 % (p<0.001). Velocity of horizontal saccade in Parkinsonian patients was 350.5±85.30 and in normal group was 493.3±79.9 (p<0.001). Differences in right eye was statistically significant (p<0.001).CONCLUSION: This study showed that patients with Parkinson’s disease manifest saccadic deficits. This suggests dopaminergic control of these ocular movements. We can consider these differences as the characteristic of Parkinson disorder in diagnosis and treatment.
format	article
author	R Hosseinabadi, AR Sheibanizadeh GH.A shahidi A gholampor M Shahidi
author_facet	R Hosseinabadi, AR Sheibanizadeh GH.A shahidi A gholampor M Shahidi
author_sort	R Hosseinabadi,
title	Comparison of Equilibrium Deficits in Idiopathic Parkinson’s Disease with Normal Subjects Using Videonystagmography
title_short	Comparison of Equilibrium Deficits in Idiopathic Parkinson’s Disease with Normal Subjects Using Videonystagmography
title_full	Comparison of Equilibrium Deficits in Idiopathic Parkinson’s Disease with Normal Subjects Using Videonystagmography
title_fullStr	Comparison of Equilibrium Deficits in Idiopathic Parkinson’s Disease with Normal Subjects Using Videonystagmography
title_full_unstemmed	Comparison of Equilibrium Deficits in Idiopathic Parkinson’s Disease with Normal Subjects Using Videonystagmography
title_sort	comparison of equilibrium deficits in idiopathic parkinson’s disease with normal subjects using videonystagmography
publisher	Babol University of Medical Sciences
publishDate	2009
url	https://doaj.org/article/0894fba80a8541efb741e9fb90f457ba
work_keys_str_mv	AT rhosseinabadi comparisonofequilibriumdeficitsinidiopathicparkinsonsdiseasewithnormalsubjectsusingvideonystagmography AT arsheibanizadeh comparisonofequilibriumdeficitsinidiopathicparkinsonsdiseasewithnormalsubjectsusingvideonystagmography AT ghashahidi comparisonofequilibriumdeficitsinidiopathicparkinsonsdiseasewithnormalsubjectsusingvideonystagmography AT agholampor comparisonofequilibriumdeficitsinidiopathicparkinsonsdiseasewithnormalsubjectsusingvideonystagmography AT mshahidi comparisonofequilibriumdeficitsinidiopathicparkinsonsdiseasewithnormalsubjectsusingvideonystagmography
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Comparison of Equilibrium Deficits in Idiopathic Parkinson’s Disease with Normal Subjects Using Videonystagmography

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