Molecular Basis for <named-content content-type="genus-species">Bordetella pertussis</named-content> Interference with Complement, Coagulation, Fibrinolytic, and Contact Activation Systems: the Cryo-EM Structure of the Vag8-C1 Inhibitor Complex
ABSTRACT Complement, contact activation, coagulation, and fibrinolysis are serum protein cascades that need strict regulation to maintain human health. Serum glycoprotein, a C1 inhibitor (C1-INH), is a key regulator (inhibitor) of serine proteases of all the above-mentioned pathways. Recently, an au...
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Main Authors: | , , , , , , |
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Format: | article |
Language: | EN |
Published: |
American Society for Microbiology
2021
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Subjects: | |
Online Access: | https://doaj.org/article/089a29c6c6894167ac20a9fe9aa84830 |
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