Design and Synthesis of Novel Betulin Derivatives Containing Thio-/Semicarbazone Moieties as Apoptotic Inducers through Mitochindria-Related Pathways
Two new series of betulin derivatives with semicarbazone (<b>7a</b>–<b>g</b>) or thiosemicarbazone (<b>8a</b>–<b>g</b>) groups at the C-28 position were synthesized. All compounds were evaluated for their in vitro cytotoxicities in human hepatocellular...
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Autores principales: | Jiafeng Wang, Jiale Wu, Yinglong Han, Jie Zhang, Yu Lin, Haijun Wang, Jing Wang, Jicheng Liu, Ming Bu |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
MDPI AG
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/089ba256ef8142eab819af0367c6873a |
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