PLASMODIUM VIVAX MALARIA: CLINICAL COURSE AND FREQUENCY OF RESISTANCE AGAINST CHLOROQUINE

Objective: To determine frequency of chlorolquine resistant plasmodium vivax and to observe clinical behavior of vivax malaria in our setup. Study Design: Prospective observational study. Place and Duration of Study: Combined Military Hospital Tarbela, from Jun 2014 to Jan 2015. Methodology...

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Autores principales:	Muhammad Asif Nizami, Adnan Khan, Sami Wahid
Formato:	article
Lenguaje:	EN
Publicado:	Army Medical College Rawalpindi 2021
Materias:	chloroquine malaria plasmodium vivax resistance Medicine R Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/089d2448645a40bca965846c50202095
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spelling	oai:doaj.org-article:089d2448645a40bca965846c502020952021-12-02T16:32:53ZPLASMODIUM VIVAX MALARIA: CLINICAL COURSE AND FREQUENCY OF RESISTANCE AGAINST CHLOROQUINE0030-96482411-8842https://doaj.org/article/089d2448645a40bca965846c502020952021-02-01T00:00:00Zhttps://pafmj.org/index.php/PAFMJ/article/view/6363https://doaj.org/toc/0030-9648https://doaj.org/toc/2411-8842Objective: To determine frequency of chlorolquine resistant plasmodium vivax and to observe clinical behavior of vivax malaria in our setup. Study Design: Prospective observational study. Place and Duration of Study: Combined Military Hospital Tarbela, from Jun 2014 to Jan 2015. Methodology: One hundred and twenty patients with smear confirmed plasmodium vivax malaria were included. Demographics (age and gender) and response to chloroquine as per epidemiologic definition to resistance were collected in all cases. Patients were observed closely in indoor for any clinical evidence of complications associated with vivax malaria as reported in literature. Frequencies for leucopenia and thrombocytopenia were noted. Results: Around two third (69%) patients were males with mean age of 27.67 (SD=6.85) years. Two patients showed resistance against chloroquine and rest of the patients had normal response. Seventy percent of patients had thrombocytopenia and 39% had leucopenia. All patients had clinically benign course of illness without any end organ damage. Conclusion: In patients with plasmodium vivax malaria, chloroquine resistance is infrequent and clinical course is benign in study population. Keywords: , ,, .Muhammad Asif NizamiAdnan KhanSami WahidArmy Medical College Rawalpindiarticlechloroquinemalariaplasmodium vivaxresistanceMedicineRMedicine (General)R5-920ENPakistan Armed Forces Medical Journal, Vol 71, Iss 1, Pp 196-200 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	chloroquine malaria plasmodium vivax resistance Medicine R Medicine (General) R5-920
spellingShingle	chloroquine malaria plasmodium vivax resistance Medicine R Medicine (General) R5-920 Muhammad Asif Nizami Adnan Khan Sami Wahid PLASMODIUM VIVAX MALARIA: CLINICAL COURSE AND FREQUENCY OF RESISTANCE AGAINST CHLOROQUINE
description	Objective: To determine frequency of chlorolquine resistant plasmodium vivax and to observe clinical behavior of vivax malaria in our setup. Study Design: Prospective observational study. Place and Duration of Study: Combined Military Hospital Tarbela, from Jun 2014 to Jan 2015. Methodology: One hundred and twenty patients with smear confirmed plasmodium vivax malaria were included. Demographics (age and gender) and response to chloroquine as per epidemiologic definition to resistance were collected in all cases. Patients were observed closely in indoor for any clinical evidence of complications associated with vivax malaria as reported in literature. Frequencies for leucopenia and thrombocytopenia were noted. Results: Around two third (69%) patients were males with mean age of 27.67 (SD=6.85) years. Two patients showed resistance against chloroquine and rest of the patients had normal response. Seventy percent of patients had thrombocytopenia and 39% had leucopenia. All patients had clinically benign course of illness without any end organ damage. Conclusion: In patients with plasmodium vivax malaria, chloroquine resistance is infrequent and clinical course is benign in study population. Keywords: , ,, .
format	article
author	Muhammad Asif Nizami Adnan Khan Sami Wahid
author_facet	Muhammad Asif Nizami Adnan Khan Sami Wahid
author_sort	Muhammad Asif Nizami
title	PLASMODIUM VIVAX MALARIA: CLINICAL COURSE AND FREQUENCY OF RESISTANCE AGAINST CHLOROQUINE
title_short	PLASMODIUM VIVAX MALARIA: CLINICAL COURSE AND FREQUENCY OF RESISTANCE AGAINST CHLOROQUINE
title_full	PLASMODIUM VIVAX MALARIA: CLINICAL COURSE AND FREQUENCY OF RESISTANCE AGAINST CHLOROQUINE
title_fullStr	PLASMODIUM VIVAX MALARIA: CLINICAL COURSE AND FREQUENCY OF RESISTANCE AGAINST CHLOROQUINE
title_full_unstemmed	PLASMODIUM VIVAX MALARIA: CLINICAL COURSE AND FREQUENCY OF RESISTANCE AGAINST CHLOROQUINE
title_sort	plasmodium vivax malaria: clinical course and frequency of resistance against chloroquine
publisher	Army Medical College Rawalpindi
publishDate	2021
url	https://doaj.org/article/089d2448645a40bca965846c50202095
work_keys_str_mv	AT muhammadasifnizami plasmodiumvivaxmalariaclinicalcourseandfrequencyofresistanceagainstchloroquine AT adnankhan plasmodiumvivaxmalariaclinicalcourseandfrequencyofresistanceagainstchloroquine AT samiwahid plasmodiumvivaxmalariaclinicalcourseandfrequencyofresistanceagainstchloroquine
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PLASMODIUM VIVAX MALARIA: CLINICAL COURSE AND FREQUENCY OF RESISTANCE AGAINST CHLOROQUINE

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