Clinical course of focal choroidal excavation in Vogt–Koyanagi–Harada disease

Yuko Nishikawa,1–3,* Kaoru Fujinami,1,2,4,5,* Ken Watanabe,1,2 Toru Noda,1,2 Kazushige Tsunoda,1,2 Kunihiko Akiyama1,2 1Department of Ophthalmology, National Hospital Organization, Tokyo Medical Center, Tokyo, Japan; 2Laboratory of Visual Physiology, National Institute of Sensory Organs,...

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Autores principales: Nishikawa Y, Fujinami K, Watanabe K, Noda T, Tsunoda K, Akiyama K
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Publicado: Dove Medical Press 2014
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Acceso en línea:https://doaj.org/article/08a77297efdf4d83895716e3e54ed2c5
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spelling oai:doaj.org-article:08a77297efdf4d83895716e3e54ed2c52021-12-02T00:25:41ZClinical course of focal choroidal excavation in Vogt–Koyanagi–Harada disease1177-5483https://doaj.org/article/08a77297efdf4d83895716e3e54ed2c52014-12-01T00:00:00Zhttp://www.dovepress.com/clinical-course-of-focal-choroidal-excavation-in-vogtndashkoyanagindas-peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483 Yuko Nishikawa,1–3,* Kaoru Fujinami,1,2,4,5,* Ken Watanabe,1,2 Toru Noda,1,2 Kazushige Tsunoda,1,2 Kunihiko Akiyama1,2 1Department of Ophthalmology, National Hospital Organization, Tokyo Medical Center, Tokyo, Japan; 2Laboratory of Visual Physiology, National Institute of Sensory Organs, National Tokyo Medical Center, Tokyo, Japan; 3Department of Ophthalmology, Osaka Medical College, Takatsuki, Osaka, Japan; 4Department of Ophthalmology, Keio University School of Medicine, Tokyo, Japan; 5UCL Institute of Ophthalmology, London, UK*These authors contributed equally to this workAbstract: We describe focal choroidal excavation (FCE) in a case of Vogt–Koyanagi–Harada (VKH) disease and compare the findings with different chorioretinal conditions. A 55-year-old man was diagnosed with VKH based on panuveitis and exudative retinal detachments. Spectral-domain optical coherence tomography demonstrated a dome-shaped protrusion with a nonconforming pattern at the fovea, which had been detected as a conforming pattern 1 year before the onset. The FCE pattern returned into a conforming pattern following corticosteroid therapy. These findings suggest that the natively existent FCE could be affected by pathophysiological changes of VKH as well as other chorioretinal conditions.Keywords: choroidal excavation, focal choroidal excavation, Vogt–Koyanagi–Harada disease, optical coherence tomographyNishikawa YFujinami KWatanabe KNoda TTsunoda KAkiyama KDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2014, Iss default, Pp 2461-2465 (2014)
institution DOAJ
collection DOAJ
language EN
topic Ophthalmology
RE1-994
spellingShingle Ophthalmology
RE1-994
Nishikawa Y
Fujinami K
Watanabe K
Noda T
Tsunoda K
Akiyama K
Clinical course of focal choroidal excavation in Vogt–Koyanagi–Harada disease
description Yuko Nishikawa,1–3,* Kaoru Fujinami,1,2,4,5,* Ken Watanabe,1,2 Toru Noda,1,2 Kazushige Tsunoda,1,2 Kunihiko Akiyama1,2 1Department of Ophthalmology, National Hospital Organization, Tokyo Medical Center, Tokyo, Japan; 2Laboratory of Visual Physiology, National Institute of Sensory Organs, National Tokyo Medical Center, Tokyo, Japan; 3Department of Ophthalmology, Osaka Medical College, Takatsuki, Osaka, Japan; 4Department of Ophthalmology, Keio University School of Medicine, Tokyo, Japan; 5UCL Institute of Ophthalmology, London, UK*These authors contributed equally to this workAbstract: We describe focal choroidal excavation (FCE) in a case of Vogt–Koyanagi–Harada (VKH) disease and compare the findings with different chorioretinal conditions. A 55-year-old man was diagnosed with VKH based on panuveitis and exudative retinal detachments. Spectral-domain optical coherence tomography demonstrated a dome-shaped protrusion with a nonconforming pattern at the fovea, which had been detected as a conforming pattern 1 year before the onset. The FCE pattern returned into a conforming pattern following corticosteroid therapy. These findings suggest that the natively existent FCE could be affected by pathophysiological changes of VKH as well as other chorioretinal conditions.Keywords: choroidal excavation, focal choroidal excavation, Vogt–Koyanagi–Harada disease, optical coherence tomography
format article
author Nishikawa Y
Fujinami K
Watanabe K
Noda T
Tsunoda K
Akiyama K
author_facet Nishikawa Y
Fujinami K
Watanabe K
Noda T
Tsunoda K
Akiyama K
author_sort Nishikawa Y
title Clinical course of focal choroidal excavation in Vogt–Koyanagi–Harada disease
title_short Clinical course of focal choroidal excavation in Vogt–Koyanagi–Harada disease
title_full Clinical course of focal choroidal excavation in Vogt–Koyanagi–Harada disease
title_fullStr Clinical course of focal choroidal excavation in Vogt–Koyanagi–Harada disease
title_full_unstemmed Clinical course of focal choroidal excavation in Vogt–Koyanagi–Harada disease
title_sort clinical course of focal choroidal excavation in vogt–koyanagi–harada disease
publisher Dove Medical Press
publishDate 2014
url https://doaj.org/article/08a77297efdf4d83895716e3e54ed2c5
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