The clinical utility of new combination phenylephrine/ketorolac injection in cataract surgery

Lola Elizabeth Lawuyi, Avinash Gurbaxani Moorfields Eye Hospital Dubai, Dubai, UAE Abstract: The maintenance of mydriasis throughout cataract extraction surgery and the control of ocular inflammation are crucial for successful surgical outcomes. The development of miosis during cataract surgery co...

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Autores principales: Lawuyi LE, Gurbaxani A
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Lenguaje:EN
Publicado: Dove Medical Press 2015
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Acceso en línea:https://doaj.org/article/08cccd6c63144f409cb13d41c781902d
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spelling oai:doaj.org-article:08cccd6c63144f409cb13d41c781902d2021-12-02T00:24:50ZThe clinical utility of new combination phenylephrine/ketorolac injection in cataract surgery1177-5483https://doaj.org/article/08cccd6c63144f409cb13d41c781902d2015-07-01T00:00:00Zhttp://www.dovepress.com/the-clinical-utility-of-new-combination-phenylephrineketorolac-injecti-peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483Lola Elizabeth Lawuyi, Avinash Gurbaxani Moorfields Eye Hospital Dubai, Dubai, UAE Abstract: The maintenance of mydriasis throughout cataract extraction surgery and the control of ocular inflammation are crucial for successful surgical outcomes. The development of miosis during cataract surgery compromises the visualization of the surgical field and working space for surgeons. This may lead to complications that include posterior capsular tear and associated vitreous loss, longer surgical time, and postoperative inflammation. Postoperative inflammation is often uncomfortable and frustrating for patients. It causes pain, redness, and photophobia. This compromises the best-uncorrected vision following surgery and often leads to multiple clinic visits. This article examines the literature published on the current treatments used to manage mydriasis, pain, and inflammation in cataract extraction surgery. Combination phenylephrine/ketorolac injection offers an exciting new class of medication for use in cataract surgery. With the recent approval of Omidria™ (combination of phenylephrine 1% and ketorolac 0.3%) by the US Food and Drug Administration (FDA) for intraocular use, we review the clinical utility of this new combination injection in cataract surgery. PubMed, MEDLINE, and conference proceedings were searched for the relevant literature using a combination of the following search terms: cataract extraction surgery, pupil dilation (mydriasis), miosis, phenylephrine, ketorolac, Omidria™, intracameral mydriatic. Relevant articles were reviewed and their references checked for further relevant literature. All abstracts were reviewed and full texts retrieved where available. Keywords: cataract extraction surgery, ketorolac, mydriasis, miosis, Omidria™, phenylephrineLawuyi LEGurbaxani ADove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2015, Iss default, Pp 1249-1254 (2015)
institution DOAJ
collection DOAJ
language EN
topic Ophthalmology
RE1-994
spellingShingle Ophthalmology
RE1-994
Lawuyi LE
Gurbaxani A
The clinical utility of new combination phenylephrine/ketorolac injection in cataract surgery
description Lola Elizabeth Lawuyi, Avinash Gurbaxani Moorfields Eye Hospital Dubai, Dubai, UAE Abstract: The maintenance of mydriasis throughout cataract extraction surgery and the control of ocular inflammation are crucial for successful surgical outcomes. The development of miosis during cataract surgery compromises the visualization of the surgical field and working space for surgeons. This may lead to complications that include posterior capsular tear and associated vitreous loss, longer surgical time, and postoperative inflammation. Postoperative inflammation is often uncomfortable and frustrating for patients. It causes pain, redness, and photophobia. This compromises the best-uncorrected vision following surgery and often leads to multiple clinic visits. This article examines the literature published on the current treatments used to manage mydriasis, pain, and inflammation in cataract extraction surgery. Combination phenylephrine/ketorolac injection offers an exciting new class of medication for use in cataract surgery. With the recent approval of Omidria™ (combination of phenylephrine 1% and ketorolac 0.3%) by the US Food and Drug Administration (FDA) for intraocular use, we review the clinical utility of this new combination injection in cataract surgery. PubMed, MEDLINE, and conference proceedings were searched for the relevant literature using a combination of the following search terms: cataract extraction surgery, pupil dilation (mydriasis), miosis, phenylephrine, ketorolac, Omidria™, intracameral mydriatic. Relevant articles were reviewed and their references checked for further relevant literature. All abstracts were reviewed and full texts retrieved where available. Keywords: cataract extraction surgery, ketorolac, mydriasis, miosis, Omidria™, phenylephrine
format article
author Lawuyi LE
Gurbaxani A
author_facet Lawuyi LE
Gurbaxani A
author_sort Lawuyi LE
title The clinical utility of new combination phenylephrine/ketorolac injection in cataract surgery
title_short The clinical utility of new combination phenylephrine/ketorolac injection in cataract surgery
title_full The clinical utility of new combination phenylephrine/ketorolac injection in cataract surgery
title_fullStr The clinical utility of new combination phenylephrine/ketorolac injection in cataract surgery
title_full_unstemmed The clinical utility of new combination phenylephrine/ketorolac injection in cataract surgery
title_sort clinical utility of new combination phenylephrine/ketorolac injection in cataract surgery
publisher Dove Medical Press
publishDate 2015
url https://doaj.org/article/08cccd6c63144f409cb13d41c781902d
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