Acupuncture versus Lornoxicam in the Treatment of Acute Renal Colic: A Randomized Controlled Trial
Xiaohua Zhang,1,* Xinguo Liu,2,* Qiongxiang Ye,2 Xunbao Wang,2 Jinjun Chen,2 Zhiyong Wang,2 Pengfei Zhao,2 Baozhou Tao,2 Guoping Xu,2 Wanfeng Xu,2 Kan Wu,2 Yao Xiao,3 Li Yang,1 Junqiang Tian,1 Juan Wang,1 Zhilong Dong,1 Zhiping Wang1 1Institute of Urology, Lanzhou University Second H...
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Dove Medical Press
2021
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oai:doaj.org-article:08cfc1cedf9547cba6f4dcf766dedc252021-11-30T18:50:37ZAcupuncture versus Lornoxicam in the Treatment of Acute Renal Colic: A Randomized Controlled Trial1178-7090https://doaj.org/article/08cfc1cedf9547cba6f4dcf766dedc252021-11-01T00:00:00Zhttps://www.dovepress.com/acupuncture-versus-lornoxicam-in-the-treatment-of-acute-renal-colic-a--peer-reviewed-fulltext-article-JPRhttps://doaj.org/toc/1178-7090Xiaohua Zhang,1,* Xinguo Liu,2,* Qiongxiang Ye,2 Xunbao Wang,2 Jinjun Chen,2 Zhiyong Wang,2 Pengfei Zhao,2 Baozhou Tao,2 Guoping Xu,2 Wanfeng Xu,2 Kan Wu,2 Yao Xiao,3 Li Yang,1 Junqiang Tian,1 Juan Wang,1 Zhilong Dong,1 Zhiping Wang1 1Institute of Urology, Lanzhou University Second Hospital; Key Laboratory of Gansu Province for Urological Diseases; Gansu Nephro-Urological Clinical Center, Lanzhou, Gansu Province, People’s Republic of China; 2Department of Urology, Susong County People’s Hospital, Susong, Anhui Province, People’s Republic of China; 3Department of Pediatrics, Lanzhou University Second Hospital, Lanzhou, Gansu Province, People’s Republic of China*These authors contributed equally to this workCorrespondence: Zhiping Wang Email wangzplzu@163.comObjective: To compare the analgesic efficacy and safety of acupuncture and lornoxicam in acute renal colic (ARC).Design, Setting, Participant: A randomized, double-blind, parallel-controlled, single-centered trial was conducted at Susong County People’s Hospital from October 2019 to November 2020. Eighty-four patients with ARC were randomly divided into lornoxicam group (Group L) and acupuncture group (Group A). Group A was treated with acupuncture at Sanyinjiao (SP6), Yinlingquan (SP9) and normal saline, and Group L was treated with sham acupuncture at SP6, SP9 and lornoxicam.Main Outcome Measures: Visual analogue scale (VAS) scores and adverse reactions such as nausea and dizziness were recorded within 5, 10, 15, 20 and 40 minutes after treatment. The main outcome of this study was the short-term effective (STE) rate, the secondary outcome was the onset time, and the safety index was incidence of adverse reactions.Results: A total of 80 patients completed this study, including 41 patients (21 males and 20 females) in Group L and 39 patients (21 males and 18 females) in Group A. Group A exhibited lower scores versus group L after treatment (P < 0.05). The overall STE of group L was 61.00% (25/41), significantly lower than group A [84.62% (33/39)] (P < 0.001). There was no difference in the incidence of adverse reactions between group A [2.6% (1/39)] and group L [7.3% (3/41)] (P = 0.616). The ordered logistic regression analysis showed patients receiving acupuncture therapy are more likely to be cured [OR = 2.887, 95% CI: (1.190, 7.000), P = 0.019].Conclusion: Acupuncture at SP6, SP9 and intramuscular injection of lornoxicam can effectively and safely relieve ARC, but the former has faster and better analgesic effect. Moreover, the incidence of adverse reactions was similar between the two treatments. This acupuncture therapy is recommended as a complementary therapy for ARC.Keywords: acupuncture, lornoxicam, renal colic, analgesiaZhang XLiu XYe QWang XChen JWang ZZhao PTao BXu GXu WWu KXiao YYang LTian JWang JDong ZWang ZDove Medical Pressarticleacupuncturelornoxicamrenal colicanalgesiaMedicine (General)R5-920ENJournal of Pain Research, Vol Volume 14, Pp 3637-3648 (2021) |
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DOAJ |
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acupuncture lornoxicam renal colic analgesia Medicine (General) R5-920 |
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acupuncture lornoxicam renal colic analgesia Medicine (General) R5-920 Zhang X Liu X Ye Q Wang X Chen J Wang Z Zhao P Tao B Xu G Xu W Wu K Xiao Y Yang L Tian J Wang J Dong Z Wang Z Acupuncture versus Lornoxicam in the Treatment of Acute Renal Colic: A Randomized Controlled Trial |
| description |
Xiaohua Zhang,1,* Xinguo Liu,2,* Qiongxiang Ye,2 Xunbao Wang,2 Jinjun Chen,2 Zhiyong Wang,2 Pengfei Zhao,2 Baozhou Tao,2 Guoping Xu,2 Wanfeng Xu,2 Kan Wu,2 Yao Xiao,3 Li Yang,1 Junqiang Tian,1 Juan Wang,1 Zhilong Dong,1 Zhiping Wang1 1Institute of Urology, Lanzhou University Second Hospital; Key Laboratory of Gansu Province for Urological Diseases; Gansu Nephro-Urological Clinical Center, Lanzhou, Gansu Province, People’s Republic of China; 2Department of Urology, Susong County People’s Hospital, Susong, Anhui Province, People’s Republic of China; 3Department of Pediatrics, Lanzhou University Second Hospital, Lanzhou, Gansu Province, People’s Republic of China*These authors contributed equally to this workCorrespondence: Zhiping Wang Email wangzplzu@163.comObjective: To compare the analgesic efficacy and safety of acupuncture and lornoxicam in acute renal colic (ARC).Design, Setting, Participant: A randomized, double-blind, parallel-controlled, single-centered trial was conducted at Susong County People’s Hospital from October 2019 to November 2020. Eighty-four patients with ARC were randomly divided into lornoxicam group (Group L) and acupuncture group (Group A). Group A was treated with acupuncture at Sanyinjiao (SP6), Yinlingquan (SP9) and normal saline, and Group L was treated with sham acupuncture at SP6, SP9 and lornoxicam.Main Outcome Measures: Visual analogue scale (VAS) scores and adverse reactions such as nausea and dizziness were recorded within 5, 10, 15, 20 and 40 minutes after treatment. The main outcome of this study was the short-term effective (STE) rate, the secondary outcome was the onset time, and the safety index was incidence of adverse reactions.Results: A total of 80 patients completed this study, including 41 patients (21 males and 20 females) in Group L and 39 patients (21 males and 18 females) in Group A. Group A exhibited lower scores versus group L after treatment (P < 0.05). The overall STE of group L was 61.00% (25/41), significantly lower than group A [84.62% (33/39)] (P < 0.001). There was no difference in the incidence of adverse reactions between group A [2.6% (1/39)] and group L [7.3% (3/41)] (P = 0.616). The ordered logistic regression analysis showed patients receiving acupuncture therapy are more likely to be cured [OR = 2.887, 95% CI: (1.190, 7.000), P = 0.019].Conclusion: Acupuncture at SP6, SP9 and intramuscular injection of lornoxicam can effectively and safely relieve ARC, but the former has faster and better analgesic effect. Moreover, the incidence of adverse reactions was similar between the two treatments. This acupuncture therapy is recommended as a complementary therapy for ARC.Keywords: acupuncture, lornoxicam, renal colic, analgesia |
| format |
article |
| author |
Zhang X Liu X Ye Q Wang X Chen J Wang Z Zhao P Tao B Xu G Xu W Wu K Xiao Y Yang L Tian J Wang J Dong Z Wang Z |
| author_facet |
Zhang X Liu X Ye Q Wang X Chen J Wang Z Zhao P Tao B Xu G Xu W Wu K Xiao Y Yang L Tian J Wang J Dong Z Wang Z |
| author_sort |
Zhang X |
| title |
Acupuncture versus Lornoxicam in the Treatment of Acute Renal Colic: A Randomized Controlled Trial |
| title_short |
Acupuncture versus Lornoxicam in the Treatment of Acute Renal Colic: A Randomized Controlled Trial |
| title_full |
Acupuncture versus Lornoxicam in the Treatment of Acute Renal Colic: A Randomized Controlled Trial |
| title_fullStr |
Acupuncture versus Lornoxicam in the Treatment of Acute Renal Colic: A Randomized Controlled Trial |
| title_full_unstemmed |
Acupuncture versus Lornoxicam in the Treatment of Acute Renal Colic: A Randomized Controlled Trial |
| title_sort |
acupuncture versus lornoxicam in the treatment of acute renal colic: a randomized controlled trial |
| publisher |
Dove Medical Press |
| publishDate |
2021 |
| url |
https://doaj.org/article/08cfc1cedf9547cba6f4dcf766dedc25 |
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