Clinical Outcomes of Patients with Rheumatoid Arthritis Treated in a Disease Management Program: Real-World Results

Pedro Santos-Moreno,1 Paola Castillo,2 Laura Villareal,3 Carlos Pineda,4 Hugo Sandoval,5 Omaira Valencia2 1Scientific Direction, Biomab Center for Rheumatoid Arthritis, Bogotá, D.C., Colombia; 2Research Department, Biomab Center for Rheumatoid Arthritis, Bogotá, D.C., Colombia;...

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Autores principales:	Santos-Moreno P, Castillo P, Villareal L, Pineda C, Sandoval H, Valencia O
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2020
Materias:	disease management rheumatoid arthritis quality of life evidence-based practice patients Diseases of the musculoskeletal system RC925-935
Acceso en línea:	https://doaj.org/article/08d06c424a0f45dfab111ad9edc9f3ff
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spelling	oai:doaj.org-article:08d06c424a0f45dfab111ad9edc9f3ff2021-12-02T12:46:50ZClinical Outcomes of Patients with Rheumatoid Arthritis Treated in a Disease Management Program: Real-World Results1179-156Xhttps://doaj.org/article/08d06c424a0f45dfab111ad9edc9f3ff2020-11-01T00:00:00Zhttps://www.dovepress.com/clinical-outcomes-of-patients-with-rheumatoid-arthritis-treated-in-a-d-peer-reviewed-article-OARRRhttps://doaj.org/toc/1179-156XPedro Santos-Moreno,1 Paola Castillo,2 Laura Villareal,3 Carlos Pineda,4 Hugo Sandoval,5 Omaira Valencia2 1Scientific Direction, Biomab Center for Rheumatoid Arthritis, Bogotá, D.C., Colombia; 2Research Department, Biomab Center for Rheumatoid Arthritis, Bogotá, D.C., Colombia; 3Medical Direction, Biomab Center for Rheumatoid Arthritis, Bogotá, D.C., Colombia; 4Division of Musculoskeletal and Rheumatic Disorders, Instituto Nacional de Rehabilitación Luis Guillermo Ibarra Ibarra, Mexico City, Mexico; 5Sociomedical Research Unit, Instituto Nacional de Rehabilitación Luis Guillermo Ibarra Ibarra, Mexico City, MexicoCorrespondence: Omaira ValenciaResearch Department, Biomab Center for Rheumatoid Arthritis, Calle 48 #13– 86, Bogotá, D.C., ColombiaEmail o.valencia10@uniandes.edu.coBackground: Care models can affect the clinical outcome of patients with rheumatic and musculoskeletal diseases.Objective: We aimed to compare how an innovative model of a rheumatoid arthritis disease-management program can improve the clinical outcomes of patients compared to a conventional assessment approach.Methods: We performed a retrospective analysis of real-world data from clinical records of a cohort of 5078 patients diagnosed with rheumatoid arthritis who were followed up at the Center of Excellence in Rheumatoid Arthritis vs the clinical outcomes reported in the Colombian National Registry of Rheumatoid Arthritis.Results: We found significant differences in the diagnosis and follow-up between the specialized Center program and the usual care reported by the Colombian National Registry (p< 0.005), including the evaluation of rheumatoid factor, Anti-citrullinated antibodies Disease Activity Score, Health Assessment Questionnaire, number of visits to the rheumatologist, and clinical outcomes measured by the level of disease activity. In addition, when comparing the Center’s clinical outcomes – from baseline to the last follow-up, we found an improvement in the level of disease activity, with patients classified in remission increasing from 20.8% to 58.5% (p< 0.005), and a reduction in those with high disease activity from 18% to 4.7% (p< 0.005).Conclusion: Real-world evidence showed that patients with rheumatoid arthritis who underwent follow-up under an innovative disease-management model improved their clinical outcomes compared with those patients in a conventional assessment program. These results could suggest a way of improving health policies for patients with rheumatoid arthritis.Keywords: disease management, rheumatoid arthritis, quality of life, evidence-based practice, patientsSantos-Moreno PCastillo PVillareal LPineda CSandoval HValencia ODove Medical Pressarticledisease managementrheumatoid arthritisquality of lifeevidence-based practicepatientsDiseases of the musculoskeletal systemRC925-935ENOpen Access Rheumatology: Research and Reviews, Vol Volume 12, Pp 249-256 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	disease management rheumatoid arthritis quality of life evidence-based practice patients Diseases of the musculoskeletal system RC925-935
spellingShingle	disease management rheumatoid arthritis quality of life evidence-based practice patients Diseases of the musculoskeletal system RC925-935 Santos-Moreno P Castillo P Villareal L Pineda C Sandoval H Valencia O Clinical Outcomes of Patients with Rheumatoid Arthritis Treated in a Disease Management Program: Real-World Results
description	Pedro Santos-Moreno,1 Paola Castillo,2 Laura Villareal,3 Carlos Pineda,4 Hugo Sandoval,5 Omaira Valencia2 1Scientific Direction, Biomab Center for Rheumatoid Arthritis, Bogotá, D.C., Colombia; 2Research Department, Biomab Center for Rheumatoid Arthritis, Bogotá, D.C., Colombia; 3Medical Direction, Biomab Center for Rheumatoid Arthritis, Bogotá, D.C., Colombia; 4Division of Musculoskeletal and Rheumatic Disorders, Instituto Nacional de Rehabilitación Luis Guillermo Ibarra Ibarra, Mexico City, Mexico; 5Sociomedical Research Unit, Instituto Nacional de Rehabilitación Luis Guillermo Ibarra Ibarra, Mexico City, MexicoCorrespondence: Omaira ValenciaResearch Department, Biomab Center for Rheumatoid Arthritis, Calle 48 #13– 86, Bogotá, D.C., ColombiaEmail o.valencia10@uniandes.edu.coBackground: Care models can affect the clinical outcome of patients with rheumatic and musculoskeletal diseases.Objective: We aimed to compare how an innovative model of a rheumatoid arthritis disease-management program can improve the clinical outcomes of patients compared to a conventional assessment approach.Methods: We performed a retrospective analysis of real-world data from clinical records of a cohort of 5078 patients diagnosed with rheumatoid arthritis who were followed up at the Center of Excellence in Rheumatoid Arthritis vs the clinical outcomes reported in the Colombian National Registry of Rheumatoid Arthritis.Results: We found significant differences in the diagnosis and follow-up between the specialized Center program and the usual care reported by the Colombian National Registry (p< 0.005), including the evaluation of rheumatoid factor, Anti-citrullinated antibodies Disease Activity Score, Health Assessment Questionnaire, number of visits to the rheumatologist, and clinical outcomes measured by the level of disease activity. In addition, when comparing the Center’s clinical outcomes – from baseline to the last follow-up, we found an improvement in the level of disease activity, with patients classified in remission increasing from 20.8% to 58.5% (p< 0.005), and a reduction in those with high disease activity from 18% to 4.7% (p< 0.005).Conclusion: Real-world evidence showed that patients with rheumatoid arthritis who underwent follow-up under an innovative disease-management model improved their clinical outcomes compared with those patients in a conventional assessment program. These results could suggest a way of improving health policies for patients with rheumatoid arthritis.Keywords: disease management, rheumatoid arthritis, quality of life, evidence-based practice, patients
format	article
author	Santos-Moreno P Castillo P Villareal L Pineda C Sandoval H Valencia O
author_facet	Santos-Moreno P Castillo P Villareal L Pineda C Sandoval H Valencia O
author_sort	Santos-Moreno P
title	Clinical Outcomes of Patients with Rheumatoid Arthritis Treated in a Disease Management Program: Real-World Results
title_short	Clinical Outcomes of Patients with Rheumatoid Arthritis Treated in a Disease Management Program: Real-World Results
title_full	Clinical Outcomes of Patients with Rheumatoid Arthritis Treated in a Disease Management Program: Real-World Results
title_fullStr	Clinical Outcomes of Patients with Rheumatoid Arthritis Treated in a Disease Management Program: Real-World Results
title_full_unstemmed	Clinical Outcomes of Patients with Rheumatoid Arthritis Treated in a Disease Management Program: Real-World Results
title_sort	clinical outcomes of patients with rheumatoid arthritis treated in a disease management program: real-world results
publisher	Dove Medical Press
publishDate	2020
url	https://doaj.org/article/08d06c424a0f45dfab111ad9edc9f3ff
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Clinical Outcomes of Patients with Rheumatoid Arthritis Treated in a Disease Management Program: Real-World Results

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