Short-chain fatty acids regulate systemic bone mass and protect from pathological bone loss

Short-chain fatty acids (SCFA) are a main class of metabolites derived from fermentation of dietary fibre in the intestine. Here, the authors show that dietary administration of SCFA is associated with inhibition of osteoclast differentiation, increased bone mass, and reduced pathological bone loss...

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Autores principales:	Sébastien Lucas, Yasunori Omata, Jörg Hofmann, Martin Böttcher, Aida Iljazovic, Kerstin Sarter, Olivia Albrecht, Oscar Schulz, Brenda Krishnacoumar, Gerhard Krönke, Martin Herrmann, Dimitrios Mougiakakos, Till Strowig, Georg Schett, Mario M. Zaiss
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/08d47d8f88be44b4963529fd15837407
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spelling	oai:doaj.org-article:08d47d8f88be44b4963529fd158374072021-12-02T14:39:46ZShort-chain fatty acids regulate systemic bone mass and protect from pathological bone loss10.1038/s41467-017-02490-42041-1723https://doaj.org/article/08d47d8f88be44b4963529fd158374072018-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-02490-4https://doaj.org/toc/2041-1723Short-chain fatty acids (SCFA) are a main class of metabolites derived from fermentation of dietary fibre in the intestine. Here, the authors show that dietary administration of SCFA is associated with inhibition of osteoclast differentiation, increased bone mass, and reduced pathological bone loss in mice.Sébastien LucasYasunori OmataJörg HofmannMartin BöttcherAida IljazovicKerstin SarterOlivia AlbrechtOscar SchulzBrenda KrishnacoumarGerhard KrönkeMartin HerrmannDimitrios MougiakakosTill StrowigGeorg SchettMario M. ZaissNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Sébastien Lucas Yasunori Omata Jörg Hofmann Martin Böttcher Aida Iljazovic Kerstin Sarter Olivia Albrecht Oscar Schulz Brenda Krishnacoumar Gerhard Krönke Martin Herrmann Dimitrios Mougiakakos Till Strowig Georg Schett Mario M. Zaiss Short-chain fatty acids regulate systemic bone mass and protect from pathological bone loss
description	Short-chain fatty acids (SCFA) are a main class of metabolites derived from fermentation of dietary fibre in the intestine. Here, the authors show that dietary administration of SCFA is associated with inhibition of osteoclast differentiation, increased bone mass, and reduced pathological bone loss in mice.
format	article
author	Sébastien Lucas Yasunori Omata Jörg Hofmann Martin Böttcher Aida Iljazovic Kerstin Sarter Olivia Albrecht Oscar Schulz Brenda Krishnacoumar Gerhard Krönke Martin Herrmann Dimitrios Mougiakakos Till Strowig Georg Schett Mario M. Zaiss
author_facet	Sébastien Lucas Yasunori Omata Jörg Hofmann Martin Böttcher Aida Iljazovic Kerstin Sarter Olivia Albrecht Oscar Schulz Brenda Krishnacoumar Gerhard Krönke Martin Herrmann Dimitrios Mougiakakos Till Strowig Georg Schett Mario M. Zaiss
author_sort	Sébastien Lucas
title	Short-chain fatty acids regulate systemic bone mass and protect from pathological bone loss
title_short	Short-chain fatty acids regulate systemic bone mass and protect from pathological bone loss
title_full	Short-chain fatty acids regulate systemic bone mass and protect from pathological bone loss
title_fullStr	Short-chain fatty acids regulate systemic bone mass and protect from pathological bone loss
title_full_unstemmed	Short-chain fatty acids regulate systemic bone mass and protect from pathological bone loss
title_sort	short-chain fatty acids regulate systemic bone mass and protect from pathological bone loss
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/08d47d8f88be44b4963529fd15837407
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Short-chain fatty acids regulate systemic bone mass and protect from pathological bone loss

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