Assembly intermediates of orthoreovirus captured in the cell

Reoviridae undergo a complex assembly pathway in the host cell. Here the authors use cryo-electron tomography to visualize the assembly stages of mammalian orthoreovirus revealing a single shelled intermediate with gross similarity to an early assembly stage of a family of prokaryotic dsRNA viruses.

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Autores principales:	Geoff Sutton, Dapeng Sun, Xiaofeng Fu, Abhay Kotecha, Corey W. Hecksel, Daniel K. Clare, Peijun Zhang, David I. Stuart, Mark Boyce
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/08db4ba63126425986073b664fcf412b
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spelling	oai:doaj.org-article:08db4ba63126425986073b664fcf412b2021-12-02T14:54:51ZAssembly intermediates of orthoreovirus captured in the cell10.1038/s41467-020-18243-92041-1723https://doaj.org/article/08db4ba63126425986073b664fcf412b2020-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-18243-9https://doaj.org/toc/2041-1723Reoviridae undergo a complex assembly pathway in the host cell. Here the authors use cryo-electron tomography to visualize the assembly stages of mammalian orthoreovirus revealing a single shelled intermediate with gross similarity to an early assembly stage of a family of prokaryotic dsRNA viruses.Geoff SuttonDapeng SunXiaofeng FuAbhay KotechaCorey W. HeckselDaniel K. ClarePeijun ZhangDavid I. StuartMark BoyceNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-7 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Geoff Sutton Dapeng Sun Xiaofeng Fu Abhay Kotecha Corey W. Hecksel Daniel K. Clare Peijun Zhang David I. Stuart Mark Boyce Assembly intermediates of orthoreovirus captured in the cell
description	Reoviridae undergo a complex assembly pathway in the host cell. Here the authors use cryo-electron tomography to visualize the assembly stages of mammalian orthoreovirus revealing a single shelled intermediate with gross similarity to an early assembly stage of a family of prokaryotic dsRNA viruses.
format	article
author	Geoff Sutton Dapeng Sun Xiaofeng Fu Abhay Kotecha Corey W. Hecksel Daniel K. Clare Peijun Zhang David I. Stuart Mark Boyce
author_facet	Geoff Sutton Dapeng Sun Xiaofeng Fu Abhay Kotecha Corey W. Hecksel Daniel K. Clare Peijun Zhang David I. Stuart Mark Boyce
author_sort	Geoff Sutton
title	Assembly intermediates of orthoreovirus captured in the cell
title_short	Assembly intermediates of orthoreovirus captured in the cell
title_full	Assembly intermediates of orthoreovirus captured in the cell
title_fullStr	Assembly intermediates of orthoreovirus captured in the cell
title_full_unstemmed	Assembly intermediates of orthoreovirus captured in the cell
title_sort	assembly intermediates of orthoreovirus captured in the cell
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/08db4ba63126425986073b664fcf412b
work_keys_str_mv	AT geoffsutton assemblyintermediatesoforthoreoviruscapturedinthecell AT dapengsun assemblyintermediatesoforthoreoviruscapturedinthecell AT xiaofengfu assemblyintermediatesoforthoreoviruscapturedinthecell AT abhaykotecha assemblyintermediatesoforthoreoviruscapturedinthecell AT coreywhecksel assemblyintermediatesoforthoreoviruscapturedinthecell AT danielkclare assemblyintermediatesoforthoreoviruscapturedinthecell AT peijunzhang assemblyintermediatesoforthoreoviruscapturedinthecell AT davidistuart assemblyintermediatesoforthoreoviruscapturedinthecell AT markboyce assemblyintermediatesoforthoreoviruscapturedinthecell
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Assembly intermediates of orthoreovirus captured in the cell

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