Deployable CRISPR-Cas13a diagnostic tools to detect and report Ebola and Lassa virus cases in real-time
Outbreaks of viral hemorrhagic fevers highlight the need for sensitive, field-deployable diagnostics. Here the authors present a CRISPR-based SHERLOCK platform with field protocol and mobile app for Ebola and Lassa fever outbreaks.
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Nature Portfolio
2020
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oai:doaj.org-article:08e45296a0194caf8c3263c4c6cc81b02021-12-02T17:08:30ZDeployable CRISPR-Cas13a diagnostic tools to detect and report Ebola and Lassa virus cases in real-time10.1038/s41467-020-17994-92041-1723https://doaj.org/article/08e45296a0194caf8c3263c4c6cc81b02020-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-17994-9https://doaj.org/toc/2041-1723Outbreaks of viral hemorrhagic fevers highlight the need for sensitive, field-deployable diagnostics. Here the authors present a CRISPR-based SHERLOCK platform with field protocol and mobile app for Ebola and Lassa fever outbreaks.Kayla G. BarnesAnna E. LachenauerAdam NitidoSameed SiddiquiRobin GrossBrett BeitzelKatherine J. SiddleCatherine A. FreijeBonnie Dighero-KempSamar B. MehtaAmber CarterJessica UwanibeFehintola AjogbasileTestimony OlumadeIkponmwosa OdiaJohn Demby SandiMambu MomohHayden C. MetskyChloe K. BoehmAaron E. LinMolly KemballDaniel J. ParkLuis BrancoMatt BoisenBrian SullivanMihret F. AmareAbdulwasiu B. TiamiyuZahra F. ParkerMichael IroezinduDonald S. GrantKayvon ModjarradCameron MyhrvoldRobert F. GarryGustavo PalaciosLisa E. HensleyStephen F. SchaffnerChristian T. HappiAndres ColubriPardis C. SabetiNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-10 (2020) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Science Q |
| spellingShingle |
Science Q Kayla G. Barnes Anna E. Lachenauer Adam Nitido Sameed Siddiqui Robin Gross Brett Beitzel Katherine J. Siddle Catherine A. Freije Bonnie Dighero-Kemp Samar B. Mehta Amber Carter Jessica Uwanibe Fehintola Ajogbasile Testimony Olumade Ikponmwosa Odia John Demby Sandi Mambu Momoh Hayden C. Metsky Chloe K. Boehm Aaron E. Lin Molly Kemball Daniel J. Park Luis Branco Matt Boisen Brian Sullivan Mihret F. Amare Abdulwasiu B. Tiamiyu Zahra F. Parker Michael Iroezindu Donald S. Grant Kayvon Modjarrad Cameron Myhrvold Robert F. Garry Gustavo Palacios Lisa E. Hensley Stephen F. Schaffner Christian T. Happi Andres Colubri Pardis C. Sabeti Deployable CRISPR-Cas13a diagnostic tools to detect and report Ebola and Lassa virus cases in real-time |
| description |
Outbreaks of viral hemorrhagic fevers highlight the need for sensitive, field-deployable diagnostics. Here the authors present a CRISPR-based SHERLOCK platform with field protocol and mobile app for Ebola and Lassa fever outbreaks. |
| format |
article |
| author |
Kayla G. Barnes Anna E. Lachenauer Adam Nitido Sameed Siddiqui Robin Gross Brett Beitzel Katherine J. Siddle Catherine A. Freije Bonnie Dighero-Kemp Samar B. Mehta Amber Carter Jessica Uwanibe Fehintola Ajogbasile Testimony Olumade Ikponmwosa Odia John Demby Sandi Mambu Momoh Hayden C. Metsky Chloe K. Boehm Aaron E. Lin Molly Kemball Daniel J. Park Luis Branco Matt Boisen Brian Sullivan Mihret F. Amare Abdulwasiu B. Tiamiyu Zahra F. Parker Michael Iroezindu Donald S. Grant Kayvon Modjarrad Cameron Myhrvold Robert F. Garry Gustavo Palacios Lisa E. Hensley Stephen F. Schaffner Christian T. Happi Andres Colubri Pardis C. Sabeti |
| author_facet |
Kayla G. Barnes Anna E. Lachenauer Adam Nitido Sameed Siddiqui Robin Gross Brett Beitzel Katherine J. Siddle Catherine A. Freije Bonnie Dighero-Kemp Samar B. Mehta Amber Carter Jessica Uwanibe Fehintola Ajogbasile Testimony Olumade Ikponmwosa Odia John Demby Sandi Mambu Momoh Hayden C. Metsky Chloe K. Boehm Aaron E. Lin Molly Kemball Daniel J. Park Luis Branco Matt Boisen Brian Sullivan Mihret F. Amare Abdulwasiu B. Tiamiyu Zahra F. Parker Michael Iroezindu Donald S. Grant Kayvon Modjarrad Cameron Myhrvold Robert F. Garry Gustavo Palacios Lisa E. Hensley Stephen F. Schaffner Christian T. Happi Andres Colubri Pardis C. Sabeti |
| author_sort |
Kayla G. Barnes |
| title |
Deployable CRISPR-Cas13a diagnostic tools to detect and report Ebola and Lassa virus cases in real-time |
| title_short |
Deployable CRISPR-Cas13a diagnostic tools to detect and report Ebola and Lassa virus cases in real-time |
| title_full |
Deployable CRISPR-Cas13a diagnostic tools to detect and report Ebola and Lassa virus cases in real-time |
| title_fullStr |
Deployable CRISPR-Cas13a diagnostic tools to detect and report Ebola and Lassa virus cases in real-time |
| title_full_unstemmed |
Deployable CRISPR-Cas13a diagnostic tools to detect and report Ebola and Lassa virus cases in real-time |
| title_sort |
deployable crispr-cas13a diagnostic tools to detect and report ebola and lassa virus cases in real-time |
| publisher |
Nature Portfolio |
| publishDate |
2020 |
| url |
https://doaj.org/article/08e45296a0194caf8c3263c4c6cc81b0 |
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