Substantial outcome improvement using a refined pilocarpine mouse model of temporal lobe epilepsy
Systemic pilocarpine treatment is one of the most reliable means of inducing temporal lobe epilepsy (TLE). However, the traditional pilocarpine injection protocol using mice was associated with a high death rate, possibly because of cardiorespiratory collapse following status epilepticus (SE). To pr...
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Autores principales: | Alexandre Vigier, Nicolas Partouche, François J. Michel, Valérie Crépel, Thomas Marissal |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/08ebf41de9724880a1f0d534eab0d80b |
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