MicroRNA genes and their target 3'-untranslated regions are infrequently somatically mutated in ovarian cancers.
MicroRNAs are key regulators of gene expression and have been shown to have altered expression in a variety of cancer types, including epithelial ovarian cancer. MiRNA function is most often achieved through binding to the 3'-untranslated region of the target protein coding gene. Mutation scree...
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Auteurs principaux: | Georgina L Ryland, Jennifer L Bearfoot, Maria A Doyle, Samantha E Boyle, David Y H Choong, Simone M Rowley, Australian Ovarian Cancer Study Group, Richard W Tothill, Kylie L Gorringe, Ian G Campbell |
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Format: | article |
Langue: | EN |
Publié: |
Public Library of Science (PLoS)
2012
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Sujets: | |
Accès en ligne: | https://doaj.org/article/08ec2f5448d14f08b23bc274d1d87f50 |
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