S. pombe kinesins-8 promote both nucleation and catastrophe of microtubules.

The kinesins-8 were originally thought to be microtubule depolymerases, but are now emerging as more versatile catalysts of microtubule dynamics. We show here that S. pombe Klp5-436 and Klp6-440 are non-processive plus-end-directed motors whose in vitro velocities on S. pombe microtubules at 7 and 2...

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Autores principales: Muriel Erent, Douglas R Drummond, Robert A Cross
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
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Acceso en línea:https://doaj.org/article/08f0e54cb3c84de9927429210b84e2cc
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