The effect of eligibility for antiretroviral therapy on body mass index and blood pressure in KwaZulu-Natal, South Africa

Abstract We use a regression discontinuity design to estimate the causal effect of antiretroviral therapy (ART) eligibility according to national treatment guidelines of South Africa on two risk factors for cardiovascular disease, body mass index (BMI) and blood pressure. We combine survey data coll...

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Autores principales:	Aditi Kuber, Anna Reuter, Pascal Geldsetzer, Natsayi Chimbindi, Mosa Moshabela, Frank Tanser, Till Bärnighausen, Sebastian Vollmer
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/08f3abab57694728b9633a8d6d02e2b1
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spelling	oai:doaj.org-article:08f3abab57694728b9633a8d6d02e2b12021-12-02T16:17:34ZThe effect of eligibility for antiretroviral therapy on body mass index and blood pressure in KwaZulu-Natal, South Africa10.1038/s41598-021-94057-z2045-2322https://doaj.org/article/08f3abab57694728b9633a8d6d02e2b12021-07-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-94057-zhttps://doaj.org/toc/2045-2322Abstract We use a regression discontinuity design to estimate the causal effect of antiretroviral therapy (ART) eligibility according to national treatment guidelines of South Africa on two risk factors for cardiovascular disease, body mass index (BMI) and blood pressure. We combine survey data collected in 2010 in KwaZulu-Natal, South Africa, with clinical data on ART. We find that early ART eligibility significantly reduces systolic and diastolic blood pressure. We do not find any significant effects on BMI. The effect on blood pressure can be detected up to three years after becoming eligible for ART.Aditi KuberAnna ReuterPascal GeldsetzerNatsayi ChimbindiMosa MoshabelaFrank TanserTill BärnighausenSebastian VollmerNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Aditi Kuber Anna Reuter Pascal Geldsetzer Natsayi Chimbindi Mosa Moshabela Frank Tanser Till Bärnighausen Sebastian Vollmer The effect of eligibility for antiretroviral therapy on body mass index and blood pressure in KwaZulu-Natal, South Africa
description	Abstract We use a regression discontinuity design to estimate the causal effect of antiretroviral therapy (ART) eligibility according to national treatment guidelines of South Africa on two risk factors for cardiovascular disease, body mass index (BMI) and blood pressure. We combine survey data collected in 2010 in KwaZulu-Natal, South Africa, with clinical data on ART. We find that early ART eligibility significantly reduces systolic and diastolic blood pressure. We do not find any significant effects on BMI. The effect on blood pressure can be detected up to three years after becoming eligible for ART.
format	article
author	Aditi Kuber Anna Reuter Pascal Geldsetzer Natsayi Chimbindi Mosa Moshabela Frank Tanser Till Bärnighausen Sebastian Vollmer
author_facet	Aditi Kuber Anna Reuter Pascal Geldsetzer Natsayi Chimbindi Mosa Moshabela Frank Tanser Till Bärnighausen Sebastian Vollmer
author_sort	Aditi Kuber
title	The effect of eligibility for antiretroviral therapy on body mass index and blood pressure in KwaZulu-Natal, South Africa
title_short	The effect of eligibility for antiretroviral therapy on body mass index and blood pressure in KwaZulu-Natal, South Africa
title_full	The effect of eligibility for antiretroviral therapy on body mass index and blood pressure in KwaZulu-Natal, South Africa
title_fullStr	The effect of eligibility for antiretroviral therapy on body mass index and blood pressure in KwaZulu-Natal, South Africa
title_full_unstemmed	The effect of eligibility for antiretroviral therapy on body mass index and blood pressure in KwaZulu-Natal, South Africa
title_sort	effect of eligibility for antiretroviral therapy on body mass index and blood pressure in kwazulu-natal, south africa
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/08f3abab57694728b9633a8d6d02e2b1
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The effect of eligibility for antiretroviral therapy on body mass index and blood pressure in KwaZulu-Natal, South Africa

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