Epigenome-wide analysis of DNA methylation and coronary heart disease: a nested case-control study

Epigenome-wide analysis of DNA methylation and coronary heart disease: a nested case-control study

Background: Identifying environmentally responsive genetic loci where DNA methylation is associated with coronary heart disease (CHD) may reveal novel pathways or therapeutic targets for CHD. We conducted the first prospective epigenome-wide analysis of DNA methylation in relation to incident CHD in...

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Autores principales: Jiahui Si, Songchun Yang, Dianjianyi Sun, Canqing Yu, Yu Guo, Yifei Lin, Iona Y Millwood, Robin G Walters, Ling Yang, Yiping Chen, Huaidong Du, Yujie Hua, Jingchao Liu, Junshi Chen, Zhengming Chen, Wei Chen, Jun Lv, Liming Liang, Liming Li, China Kadoorie Biobank Collaborative Group
Formato: article
Lenguaje:EN
Publicado: eLife Sciences Publications Ltd 2021
Materias:
coronary heart disease
epigenetics
DNA methylation
epidemiology
Medicine
R
Science
Q
Biology (General)
QH301-705.5
Acceso en línea:https://doaj.org/article/08f7c4351bf949d8ae138b5d15375855
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