“Stomach mass” as the first manifestation of IgG4-related disease: a case report

Abstract Background IgG4-related disease mainly manifests as organomegaly and is accompanied by tissue fibrosis (Mimori, Mod Rheumatol 29(2):213, 2019) which is frequently confused with tumour (Dawei et al., J Gastroenterol Hepatol 29(12):1375–8, 2020). There are few reports with of IgG4-related dis...

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Autores principales:	Fulong Zhang, Jing Xu, Yuandong Zhu, Qianneng Wu, Xincheng Xie, Yan Shi
Formato:	article
Lenguaje:	EN
Publicado:	BMC 2021
Materias:	IgG4-related disease Stomach tumour First manifestation Diseases of the digestive system. Gastroenterology RC799-869
Acceso en línea:	https://doaj.org/article/08f844f11a7e4c1e8e57f13245b4742c
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spelling	oai:doaj.org-article:08f844f11a7e4c1e8e57f13245b4742c2021-11-28T12:14:57Z“Stomach mass” as the first manifestation of IgG4-related disease: a case report10.1186/s12876-021-02013-y1471-230Xhttps://doaj.org/article/08f844f11a7e4c1e8e57f13245b4742c2021-11-01T00:00:00Zhttps://doi.org/10.1186/s12876-021-02013-yhttps://doaj.org/toc/1471-230XAbstract Background IgG4-related disease mainly manifests as organomegaly and is accompanied by tissue fibrosis (Mimori, Mod Rheumatol 29(2):213, 2019) which is frequently confused with tumour (Dawei et al., J Gastroenterol Hepatol 29(12):1375–8, 2020). There are few reports with of IgG4-related disease with the first clinical manifestation involving the stomach. Case presentation We present the case of 46-year-old male patient with a “stomach tumour” as the first manifestation of IgG4-related disease. Gastroscopy showed a mass in the stomach, however, the pathology result was chronic inflammation with IgG4 positivity. CT scans of abdomen showed that the stomach wall was thick, the head of the pancreas was swollen, and retroperitoneal fibrosis was severe.The serum IgG4 level was 75 g/L (normal range 0.03–2.01 g/L).After treatment with methylprednisolone for one month, the symptoms were greatly relieved. Conclusions To reduce the suffering of patients and relieve their financial burden, we should consider the possibility of IgG4-related disease when the initial manifestation is a stomach mass.Fulong ZhangJing XuYuandong ZhuQianneng WuXincheng XieYan ShiBMCarticleIgG4-related diseaseStomach tumourFirst manifestationDiseases of the digestive system. GastroenterologyRC799-869ENBMC Gastroenterology, Vol 21, Iss 1, Pp 1-6 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	IgG4-related disease Stomach tumour First manifestation Diseases of the digestive system. Gastroenterology RC799-869
spellingShingle	IgG4-related disease Stomach tumour First manifestation Diseases of the digestive system. Gastroenterology RC799-869 Fulong Zhang Jing Xu Yuandong Zhu Qianneng Wu Xincheng Xie Yan Shi “Stomach mass” as the first manifestation of IgG4-related disease: a case report
description	Abstract Background IgG4-related disease mainly manifests as organomegaly and is accompanied by tissue fibrosis (Mimori, Mod Rheumatol 29(2):213, 2019) which is frequently confused with tumour (Dawei et al., J Gastroenterol Hepatol 29(12):1375–8, 2020). There are few reports with of IgG4-related disease with the first clinical manifestation involving the stomach. Case presentation We present the case of 46-year-old male patient with a “stomach tumour” as the first manifestation of IgG4-related disease. Gastroscopy showed a mass in the stomach, however, the pathology result was chronic inflammation with IgG4 positivity. CT scans of abdomen showed that the stomach wall was thick, the head of the pancreas was swollen, and retroperitoneal fibrosis was severe.The serum IgG4 level was 75 g/L (normal range 0.03–2.01 g/L).After treatment with methylprednisolone for one month, the symptoms were greatly relieved. Conclusions To reduce the suffering of patients and relieve their financial burden, we should consider the possibility of IgG4-related disease when the initial manifestation is a stomach mass.
format	article
author	Fulong Zhang Jing Xu Yuandong Zhu Qianneng Wu Xincheng Xie Yan Shi
author_facet	Fulong Zhang Jing Xu Yuandong Zhu Qianneng Wu Xincheng Xie Yan Shi
author_sort	Fulong Zhang
title	“Stomach mass” as the first manifestation of IgG4-related disease: a case report
title_short	“Stomach mass” as the first manifestation of IgG4-related disease: a case report
title_full	“Stomach mass” as the first manifestation of IgG4-related disease: a case report
title_fullStr	“Stomach mass” as the first manifestation of IgG4-related disease: a case report
title_full_unstemmed	“Stomach mass” as the first manifestation of IgG4-related disease: a case report
title_sort	“stomach mass” as the first manifestation of igg4-related disease: a case report
publisher	BMC
publishDate	2021
url	https://doaj.org/article/08f844f11a7e4c1e8e57f13245b4742c
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“Stomach mass” as the first manifestation of IgG4-related disease: a case report

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