Conformational modulation of influenza virus hemagglutinin: characterization and in vivo efficacy of monomeric form

Abstract Mutational changes that mostly occur at the head region of hemagglutinin (HA) lead to the emergence of new epidemic influenza viruses, whereas HA antigens have been modified to generate broadly neutralizing antibodies toward highly conserved epitopes in the HA stem. Interestingly, a recent...

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Auteurs principaux: Jong Hyeon Seok, Jeongwon Kim, Dan Bi Lee, Ki Joon Cho, Ji-Hye Lee, Garam Bae, Mi Sook Chung, Kyung Hyun Kim
Format: article
Langue:EN
Publié: Nature Portfolio 2017
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Accès en ligne:https://doaj.org/article/08f959aac7f047e7af6edc81ca70b117
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