Light-induced primary amines and o-nitrobenzyl alcohols cyclization as a versatile photoclick reaction for modular conjugation

Developing new click chemistry reactions for robust molecular assembly remains challenging. Here the authors report a light-induced primary amines and o-nitrobenzyl alcohols photoclick cyclization for rapid and modular functionalization of small molecules and native biomolecules, in vitro and in liv...

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Autores principales:	An-Di Guo, Dan Wei, Hui-Jun Nie, Hao Hu, Chengyuan Peng, Shao-Tong Li, Ke-Nian Yan, Bin-Shan Zhou, Lei Feng, Chao Fang, Minjia Tan, Ruimin Huang, Xiao-Hua Chen
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/08fb4fa9001b40ff9f94f7eb7bb8e194
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spelling	oai:doaj.org-article:08fb4fa9001b40ff9f94f7eb7bb8e1942021-12-02T14:41:05ZLight-induced primary amines and o-nitrobenzyl alcohols cyclization as a versatile photoclick reaction for modular conjugation10.1038/s41467-020-19274-y2041-1723https://doaj.org/article/08fb4fa9001b40ff9f94f7eb7bb8e1942020-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-19274-yhttps://doaj.org/toc/2041-1723Developing new click chemistry reactions for robust molecular assembly remains challenging. Here the authors report a light-induced primary amines and o-nitrobenzyl alcohols photoclick cyclization for rapid and modular functionalization of small molecules and native biomolecules, in vitro and in living systems.An-Di GuoDan WeiHui-Jun NieHao HuChengyuan PengShao-Tong LiKe-Nian YanBin-Shan ZhouLei FengChao FangMinjia TanRuimin HuangXiao-Hua ChenNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q An-Di Guo Dan Wei Hui-Jun Nie Hao Hu Chengyuan Peng Shao-Tong Li Ke-Nian Yan Bin-Shan Zhou Lei Feng Chao Fang Minjia Tan Ruimin Huang Xiao-Hua Chen Light-induced primary amines and o-nitrobenzyl alcohols cyclization as a versatile photoclick reaction for modular conjugation
description	Developing new click chemistry reactions for robust molecular assembly remains challenging. Here the authors report a light-induced primary amines and o-nitrobenzyl alcohols photoclick cyclization for rapid and modular functionalization of small molecules and native biomolecules, in vitro and in living systems.
format	article
author	An-Di Guo Dan Wei Hui-Jun Nie Hao Hu Chengyuan Peng Shao-Tong Li Ke-Nian Yan Bin-Shan Zhou Lei Feng Chao Fang Minjia Tan Ruimin Huang Xiao-Hua Chen
author_facet	An-Di Guo Dan Wei Hui-Jun Nie Hao Hu Chengyuan Peng Shao-Tong Li Ke-Nian Yan Bin-Shan Zhou Lei Feng Chao Fang Minjia Tan Ruimin Huang Xiao-Hua Chen
author_sort	An-Di Guo
title	Light-induced primary amines and o-nitrobenzyl alcohols cyclization as a versatile photoclick reaction for modular conjugation
title_short	Light-induced primary amines and o-nitrobenzyl alcohols cyclization as a versatile photoclick reaction for modular conjugation
title_full	Light-induced primary amines and o-nitrobenzyl alcohols cyclization as a versatile photoclick reaction for modular conjugation
title_fullStr	Light-induced primary amines and o-nitrobenzyl alcohols cyclization as a versatile photoclick reaction for modular conjugation
title_full_unstemmed	Light-induced primary amines and o-nitrobenzyl alcohols cyclization as a versatile photoclick reaction for modular conjugation
title_sort	light-induced primary amines and o-nitrobenzyl alcohols cyclization as a versatile photoclick reaction for modular conjugation
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/08fb4fa9001b40ff9f94f7eb7bb8e194
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Light-induced primary amines and o-nitrobenzyl alcohols cyclization as a versatile photoclick reaction for modular conjugation

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