Collectively stabilizing and orienting posterior migratory forces disperses cell clusters in vivo

During development, primordial germ cell clusters undergo dispersal but how cell–cell adhesion and contractility are coordinated during this process in vivo is unclear. Here, the authors show that Drosophila primordial germ cells utilize migratory forces to disperse through G-protein coupled recepto...

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Autores principales:	B. Lin, J. Luo, R. Lehmann
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/08fc4baa1ed34259b88bbc464ba58b96
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id	oai:doaj.org-article:08fc4baa1ed34259b88bbc464ba58b96
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spelling	oai:doaj.org-article:08fc4baa1ed34259b88bbc464ba58b962021-12-02T17:41:08ZCollectively stabilizing and orienting posterior migratory forces disperses cell clusters in vivo10.1038/s41467-020-18185-22041-1723https://doaj.org/article/08fc4baa1ed34259b88bbc464ba58b962020-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-18185-2https://doaj.org/toc/2041-1723During development, primordial germ cell clusters undergo dispersal but how cell–cell adhesion and contractility are coordinated during this process in vivo is unclear. Here, the authors show that Drosophila primordial germ cells utilize migratory forces to disperse through G-protein coupled receptor mediated collective guidance of front-back polarity outwards from the cluster.B. LinJ. LuoR. LehmannNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q B. Lin J. Luo R. Lehmann Collectively stabilizing and orienting posterior migratory forces disperses cell clusters in vivo
description	During development, primordial germ cell clusters undergo dispersal but how cell–cell adhesion and contractility are coordinated during this process in vivo is unclear. Here, the authors show that Drosophila primordial germ cells utilize migratory forces to disperse through G-protein coupled receptor mediated collective guidance of front-back polarity outwards from the cluster.
format	article
author	B. Lin J. Luo R. Lehmann
author_facet	B. Lin J. Luo R. Lehmann
author_sort	B. Lin
title	Collectively stabilizing and orienting posterior migratory forces disperses cell clusters in vivo
title_short	Collectively stabilizing and orienting posterior migratory forces disperses cell clusters in vivo
title_full	Collectively stabilizing and orienting posterior migratory forces disperses cell clusters in vivo
title_fullStr	Collectively stabilizing and orienting posterior migratory forces disperses cell clusters in vivo
title_full_unstemmed	Collectively stabilizing and orienting posterior migratory forces disperses cell clusters in vivo
title_sort	collectively stabilizing and orienting posterior migratory forces disperses cell clusters in vivo
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/08fc4baa1ed34259b88bbc464ba58b96
work_keys_str_mv	AT blin collectivelystabilizingandorientingposteriormigratoryforcesdispersescellclustersinvivo AT jluo collectivelystabilizingandorientingposteriormigratoryforcesdispersescellclustersinvivo AT rlehmann collectivelystabilizingandorientingposteriormigratoryforcesdispersescellclustersinvivo
_version_	1718379687592329216

Collectively stabilizing and orienting posterior migratory forces disperses cell clusters in vivo

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