Clinico-epidemiological Analysis of Adult Patients With Acute Poisoning

Background: Patients with acute poisoning sometimes require hospitalization in the Intensive Care Unit (ICU). The correct admission of these patients has resulted to lower mortality. This study compared the characteristics of adult patients with acute poisoning who were admitted to the poisoning war...

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Autores principales:	Forough Soltaninejad, Ghazal Beigi, Parastoo Golshiri, Nastaran Eizadi-Mood
Formato:	article
Lenguaje:	EN
Publicado:	Shaheed Beheshti University of Medical Sciences 2021
Materias:	poisoning intensive care unit outcomes pesticides Medicine (General) R5-920 Toxicology. Poisons RA1190-1270
Acceso en línea:	https://doi.org/10.32598/ijmtfm.v11i3.33533 https://doaj.org/article/0915f5ab688c49c5bd1d0fb1c6486f46
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spelling	oai:doaj.org-article:0915f5ab688c49c5bd1d0fb1c6486f462021-11-08T07:18:52ZClinico-epidemiological Analysis of Adult Patients With Acute Poisoninghttps://doi.org/10.32598/ijmtfm.v11i3.335332251-87622251-8770https://doaj.org/article/0915f5ab688c49c5bd1d0fb1c6486f462021-08-01T00:00:00Zhttps://journals.sbmu.ac.ir/ijmtfm/article/view/33533https://doaj.org/toc/2251-8762https://doaj.org/toc/2251-8770Background: Patients with acute poisoning sometimes require hospitalization in the Intensive Care Unit (ICU). The correct admission of these patients has resulted to lower mortality. This study compared the characteristics of adult patients with acute poisoning who were admitted to the poisoning ward and the ICU. We also determined the relevant outcome predictive factors. Methods: This cross-sectional study was conducted on adult acutely poisoned patients who were admitted to the emergency room of Khorshid Hospital affiliated with Isfahan University of Medical Sciences from October 2018 to 2019. The clinico-epidemiological variables and outcomes were compared between adult patients hospitalized in the ward (n=100) and ICU (n=100). Binary logistic regression was used for predicting the outcome factors. Results: The Mean±SE age of the study patients in the ICU and ward were 36.6±1.62 (median: 34) and 34.20±1.19 years, (median: 33, P=0.23), respectively. There was no significant difference between the study groups respecting substance dependence, alcohol and drug abuse, disease history, and the type of exposure (P>0.05). However, self-mutilation, the kind of substance, the vital signs and level of consciousness at admission, and outcomes were significantly different between the research groups (P<0.05). Variables predicting outcomes (complication/death) were as follows: gender (male) (OR: 4.51; 95%CI: 1.51-13.42; P=0.007), the kind of substance (pesticides) (OR: 8.84; 95%CI: 1.78-44.07; P=0.008), time to admission (OR: 1.04; 95%CI: 1.02-1.08; P=0.002), hypotension (OR: 14.88; 95%CI: 3.01-71.58; P=0.001), and the place of hospitalization (ward) (OR: 2.85; 95%CI: 1.23-6.62; P=0.01). Conclusion: The self-mutilation, kind of substance, vital signs, level of consciousness at admission, and outcomes were significantly different between the study patients hospitalized in the ICU, compared to the ward. Gender (male), the kind of substance (pesticides), delayed arrival times, hypotension, and the place of hospitalization (ward) were essential factors for outcome (complication/death) prediction.Forough SoltaninejadGhazal BeigiParastoo GolshiriNastaran Eizadi-MoodShaheed Beheshti University of Medical Sciencesarticlepoisoningintensive care unitoutcomespesticidesMedicine (General)R5-920Toxicology. PoisonsRA1190-1270ENInternational Journal of Medical Toxicology and Forensic Medicine, Vol 11, Iss 3, p 33533 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	poisoning intensive care unit outcomes pesticides Medicine (General) R5-920 Toxicology. Poisons RA1190-1270
spellingShingle	poisoning intensive care unit outcomes pesticides Medicine (General) R5-920 Toxicology. Poisons RA1190-1270 Forough Soltaninejad Ghazal Beigi Parastoo Golshiri Nastaran Eizadi-Mood Clinico-epidemiological Analysis of Adult Patients With Acute Poisoning
description	Background: Patients with acute poisoning sometimes require hospitalization in the Intensive Care Unit (ICU). The correct admission of these patients has resulted to lower mortality. This study compared the characteristics of adult patients with acute poisoning who were admitted to the poisoning ward and the ICU. We also determined the relevant outcome predictive factors. Methods: This cross-sectional study was conducted on adult acutely poisoned patients who were admitted to the emergency room of Khorshid Hospital affiliated with Isfahan University of Medical Sciences from October 2018 to 2019. The clinico-epidemiological variables and outcomes were compared between adult patients hospitalized in the ward (n=100) and ICU (n=100). Binary logistic regression was used for predicting the outcome factors. Results: The Mean±SE age of the study patients in the ICU and ward were 36.6±1.62 (median: 34) and 34.20±1.19 years, (median: 33, P=0.23), respectively. There was no significant difference between the study groups respecting substance dependence, alcohol and drug abuse, disease history, and the type of exposure (P>0.05). However, self-mutilation, the kind of substance, the vital signs and level of consciousness at admission, and outcomes were significantly different between the research groups (P<0.05). Variables predicting outcomes (complication/death) were as follows: gender (male) (OR: 4.51; 95%CI: 1.51-13.42; P=0.007), the kind of substance (pesticides) (OR: 8.84; 95%CI: 1.78-44.07; P=0.008), time to admission (OR: 1.04; 95%CI: 1.02-1.08; P=0.002), hypotension (OR: 14.88; 95%CI: 3.01-71.58; P=0.001), and the place of hospitalization (ward) (OR: 2.85; 95%CI: 1.23-6.62; P=0.01). Conclusion: The self-mutilation, kind of substance, vital signs, level of consciousness at admission, and outcomes were significantly different between the study patients hospitalized in the ICU, compared to the ward. Gender (male), the kind of substance (pesticides), delayed arrival times, hypotension, and the place of hospitalization (ward) were essential factors for outcome (complication/death) prediction.
format	article
author	Forough Soltaninejad Ghazal Beigi Parastoo Golshiri Nastaran Eizadi-Mood
author_facet	Forough Soltaninejad Ghazal Beigi Parastoo Golshiri Nastaran Eizadi-Mood
author_sort	Forough Soltaninejad
title	Clinico-epidemiological Analysis of Adult Patients With Acute Poisoning
title_short	Clinico-epidemiological Analysis of Adult Patients With Acute Poisoning
title_full	Clinico-epidemiological Analysis of Adult Patients With Acute Poisoning
title_fullStr	Clinico-epidemiological Analysis of Adult Patients With Acute Poisoning
title_full_unstemmed	Clinico-epidemiological Analysis of Adult Patients With Acute Poisoning
title_sort	clinico-epidemiological analysis of adult patients with acute poisoning
publisher	Shaheed Beheshti University of Medical Sciences
publishDate	2021
url	https://doi.org/10.32598/ijmtfm.v11i3.33533 https://doaj.org/article/0915f5ab688c49c5bd1d0fb1c6486f46
work_keys_str_mv	AT foroughsoltaninejad clinicoepidemiologicalanalysisofadultpatientswithacutepoisoning AT ghazalbeigi clinicoepidemiologicalanalysisofadultpatientswithacutepoisoning AT parastoogolshiri clinicoepidemiologicalanalysisofadultpatientswithacutepoisoning AT nastaraneizadimood clinicoepidemiologicalanalysisofadultpatientswithacutepoisoning
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Clinico-epidemiological Analysis of Adult Patients With Acute Poisoning

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