The feasibility of pancreatic duct stenting using a novel 4-Fr plastic stent with a 0.025-in. guidewire

Abstract Pancreatic duct stenting is a well-established method for reducing post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis. However, there is no consensus on the optimal type of plastic stent. This study aimed to evaluate the feasibility and safety of a new 4-Fr plastic sten...

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Autores principales:	Kazumasa Nagai, Atsushi Sofuni, Takayoshi Tsuchiya, Kentaro Ishii, Reina Tanaka, Ryosuke Tonozuka, Shuntaro Mukai, Kenjiro Yamamoto, Yukitoshi Matsunami, Yasutsugu Asai, Takashi Kurosawa, Hiroyuki Kojima, Hirohito Minami, Toshihiro Honma, Akio Katanuma, Takao Itoi
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/0923f30a4b1b46a78b599e616ddc0063
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spelling	oai:doaj.org-article:0923f30a4b1b46a78b599e616ddc00632021-12-02T16:14:17ZThe feasibility of pancreatic duct stenting using a novel 4-Fr plastic stent with a 0.025-in. guidewire10.1038/s41598-021-92811-x2045-2322https://doaj.org/article/0923f30a4b1b46a78b599e616ddc00632021-07-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-92811-xhttps://doaj.org/toc/2045-2322Abstract Pancreatic duct stenting is a well-established method for reducing post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis. However, there is no consensus on the optimal type of plastic stent. This study aimed to evaluate the feasibility and safety of a new 4-Fr plastic stent for pancreatic duct stenting. Forty-nine consecutive patients who placed the 4-Fr stent into the pancreatic duct (4Fr group) were compared with 187 consecutive patients who placed a conventional 5-Fr stent (control group). The primary outcome was technical success. Complications rate, including post-ERCP pancreatitis (PEP) were the secondary outcomes. Propensity score matching was introduced to reduce selection bias. The technical success rate was 100% in the 4Fr group and 97.9% in the control group (p = 0.315). Post-ERCP amylase level was significantly lower in the 4-Fr group than the control group before propensity score matching (p = 0.006), though without statistical significance after propensity score matching (p = 0.298). The rate of PEP in the 4Fr group (6.1%) was lower than the control group (15.5%), though without statistical significance before (p = 0.088) and after (p = 1.00) propensity score matching. Pancreatic duct stenting using a novel 4-Fr plastic stent would be at least similar or more feasible and safe compared to the conventional plastic stent.Kazumasa NagaiAtsushi SofuniTakayoshi TsuchiyaKentaro IshiiReina TanakaRyosuke TonozukaShuntaro MukaiKenjiro YamamotoYukitoshi MatsunamiYasutsugu AsaiTakashi KurosawaHiroyuki KojimaHirohito MinamiToshihiro HonmaAkio KatanumaTakao ItoiNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-7 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Kazumasa Nagai Atsushi Sofuni Takayoshi Tsuchiya Kentaro Ishii Reina Tanaka Ryosuke Tonozuka Shuntaro Mukai Kenjiro Yamamoto Yukitoshi Matsunami Yasutsugu Asai Takashi Kurosawa Hiroyuki Kojima Hirohito Minami Toshihiro Honma Akio Katanuma Takao Itoi The feasibility of pancreatic duct stenting using a novel 4-Fr plastic stent with a 0.025-in. guidewire
description	Abstract Pancreatic duct stenting is a well-established method for reducing post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis. However, there is no consensus on the optimal type of plastic stent. This study aimed to evaluate the feasibility and safety of a new 4-Fr plastic stent for pancreatic duct stenting. Forty-nine consecutive patients who placed the 4-Fr stent into the pancreatic duct (4Fr group) were compared with 187 consecutive patients who placed a conventional 5-Fr stent (control group). The primary outcome was technical success. Complications rate, including post-ERCP pancreatitis (PEP) were the secondary outcomes. Propensity score matching was introduced to reduce selection bias. The technical success rate was 100% in the 4Fr group and 97.9% in the control group (p = 0.315). Post-ERCP amylase level was significantly lower in the 4-Fr group than the control group before propensity score matching (p = 0.006), though without statistical significance after propensity score matching (p = 0.298). The rate of PEP in the 4Fr group (6.1%) was lower than the control group (15.5%), though without statistical significance before (p = 0.088) and after (p = 1.00) propensity score matching. Pancreatic duct stenting using a novel 4-Fr plastic stent would be at least similar or more feasible and safe compared to the conventional plastic stent.
format	article
author	Kazumasa Nagai Atsushi Sofuni Takayoshi Tsuchiya Kentaro Ishii Reina Tanaka Ryosuke Tonozuka Shuntaro Mukai Kenjiro Yamamoto Yukitoshi Matsunami Yasutsugu Asai Takashi Kurosawa Hiroyuki Kojima Hirohito Minami Toshihiro Honma Akio Katanuma Takao Itoi
author_facet	Kazumasa Nagai Atsushi Sofuni Takayoshi Tsuchiya Kentaro Ishii Reina Tanaka Ryosuke Tonozuka Shuntaro Mukai Kenjiro Yamamoto Yukitoshi Matsunami Yasutsugu Asai Takashi Kurosawa Hiroyuki Kojima Hirohito Minami Toshihiro Honma Akio Katanuma Takao Itoi
author_sort	Kazumasa Nagai
title	The feasibility of pancreatic duct stenting using a novel 4-Fr plastic stent with a 0.025-in. guidewire
title_short	The feasibility of pancreatic duct stenting using a novel 4-Fr plastic stent with a 0.025-in. guidewire
title_full	The feasibility of pancreatic duct stenting using a novel 4-Fr plastic stent with a 0.025-in. guidewire
title_fullStr	The feasibility of pancreatic duct stenting using a novel 4-Fr plastic stent with a 0.025-in. guidewire
title_full_unstemmed	The feasibility of pancreatic duct stenting using a novel 4-Fr plastic stent with a 0.025-in. guidewire
title_sort	feasibility of pancreatic duct stenting using a novel 4-fr plastic stent with a 0.025-in. guidewire
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/0923f30a4b1b46a78b599e616ddc0063
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The feasibility of pancreatic duct stenting using a novel 4-Fr plastic stent with a 0.025-in. guidewire

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