Primary urethral melanoma treated sucessfully with wide excision and combination immunotherapy: Case report and review of literature

We report the rare case of a primary malignant melanoma of the urethra. An 89-year-old African American woman who was referred to our urology clinic for intermittent gross hematuria and a palpable vaginal mass of two months duration. Cystoscopy revealed a 3 cm mass in the distal urethra and urethral...

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Autores principales:	Mariela Martinez, Srinath Kotamarti, Ariel Schulman, Unni Mooppan, Jen Wang
Formato:	article
Lenguaje:	EN
Publicado:	Elsevier 2022
Materias:	Malignant melanoma Immunotherapy Oncology Urethra Diseases of the genitourinary system. Urology RC870-923
Acceso en línea:	https://doaj.org/article/092b22a2f9104384801c426ed118feab
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spelling	oai:doaj.org-article:092b22a2f9104384801c426ed118feab2021-11-22T04:25:33ZPrimary urethral melanoma treated sucessfully with wide excision and combination immunotherapy: Case report and review of literature2214-442010.1016/j.eucr.2021.101835https://doaj.org/article/092b22a2f9104384801c426ed118feab2022-01-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S2214442021002758https://doaj.org/toc/2214-4420We report the rare case of a primary malignant melanoma of the urethra. An 89-year-old African American woman who was referred to our urology clinic for intermittent gross hematuria and a palpable vaginal mass of two months duration. Cystoscopy revealed a 3 cm mass in the distal urethra and urethral meatus that was surgically resected by wide local excision. The histopathologic diagnosis was primary malignant melanoma of the urethra. The patient was subsequently treated with adjuvant EBRT and immunotherapy with nivolumab and ipilimumab. Post-treatment PET-CT showed good response to treatment and patient remained in remission at eight month follow up.Mariela MartinezSrinath KotamartiAriel SchulmanUnni MooppanJen WangElsevierarticleMalignant melanomaImmunotherapyOncologyUrethraDiseases of the genitourinary system. UrologyRC870-923ENUrology Case Reports, Vol 40, Iss , Pp 101835- (2022)
institution	DOAJ
collection	DOAJ
language	EN
topic	Malignant melanoma Immunotherapy Oncology Urethra Diseases of the genitourinary system. Urology RC870-923
spellingShingle	Malignant melanoma Immunotherapy Oncology Urethra Diseases of the genitourinary system. Urology RC870-923 Mariela Martinez Srinath Kotamarti Ariel Schulman Unni Mooppan Jen Wang Primary urethral melanoma treated sucessfully with wide excision and combination immunotherapy: Case report and review of literature
description	We report the rare case of a primary malignant melanoma of the urethra. An 89-year-old African American woman who was referred to our urology clinic for intermittent gross hematuria and a palpable vaginal mass of two months duration. Cystoscopy revealed a 3 cm mass in the distal urethra and urethral meatus that was surgically resected by wide local excision. The histopathologic diagnosis was primary malignant melanoma of the urethra. The patient was subsequently treated with adjuvant EBRT and immunotherapy with nivolumab and ipilimumab. Post-treatment PET-CT showed good response to treatment and patient remained in remission at eight month follow up.
format	article
author	Mariela Martinez Srinath Kotamarti Ariel Schulman Unni Mooppan Jen Wang
author_facet	Mariela Martinez Srinath Kotamarti Ariel Schulman Unni Mooppan Jen Wang
author_sort	Mariela Martinez
title	Primary urethral melanoma treated sucessfully with wide excision and combination immunotherapy: Case report and review of literature
title_short	Primary urethral melanoma treated sucessfully with wide excision and combination immunotherapy: Case report and review of literature
title_full	Primary urethral melanoma treated sucessfully with wide excision and combination immunotherapy: Case report and review of literature
title_fullStr	Primary urethral melanoma treated sucessfully with wide excision and combination immunotherapy: Case report and review of literature
title_full_unstemmed	Primary urethral melanoma treated sucessfully with wide excision and combination immunotherapy: Case report and review of literature
title_sort	primary urethral melanoma treated sucessfully with wide excision and combination immunotherapy: case report and review of literature
publisher	Elsevier
publishDate	2022
url	https://doaj.org/article/092b22a2f9104384801c426ed118feab
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Primary urethral melanoma treated sucessfully with wide excision and combination immunotherapy: Case report and review of literature

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