A genome-wide cross-phenotype meta-analysis of the association of blood pressure with migraine
The association between blood pressure (BP) and migraine is poorly understood. Here, the authors explore this relationship using summary-level GWAS data for BP and migraine. Cross-trait meta-analysis reveals shared loci between BP and migraine, while Mendelian randomization suggests that diastolic B...
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Nature Portfolio
2020
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oai:doaj.org-article:092c8891a7dd4e40a00ccb51a6c45afa2021-12-02T15:39:43ZA genome-wide cross-phenotype meta-analysis of the association of blood pressure with migraine10.1038/s41467-020-17002-02041-1723https://doaj.org/article/092c8891a7dd4e40a00ccb51a6c45afa2020-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-17002-0https://doaj.org/toc/2041-1723The association between blood pressure (BP) and migraine is poorly understood. Here, the authors explore this relationship using summary-level GWAS data for BP and migraine. Cross-trait meta-analysis reveals shared loci between BP and migraine, while Mendelian randomization suggests that diastolic BP specifically plays a key role in migraine susceptibility.Yanjun GuoPamela M. RistIyas DaghlasFranco GiulianiniThe International Headache Genetics ConsortiumThe 23andMe Research TeamTobias KurthDaniel I. ChasmanNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-11 (2020) |
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Science Q Yanjun Guo Pamela M. Rist Iyas Daghlas Franco Giulianini The International Headache Genetics Consortium The 23andMe Research Team Tobias Kurth Daniel I. Chasman A genome-wide cross-phenotype meta-analysis of the association of blood pressure with migraine |
description |
The association between blood pressure (BP) and migraine is poorly understood. Here, the authors explore this relationship using summary-level GWAS data for BP and migraine. Cross-trait meta-analysis reveals shared loci between BP and migraine, while Mendelian randomization suggests that diastolic BP specifically plays a key role in migraine susceptibility. |
format |
article |
author |
Yanjun Guo Pamela M. Rist Iyas Daghlas Franco Giulianini The International Headache Genetics Consortium The 23andMe Research Team Tobias Kurth Daniel I. Chasman |
author_facet |
Yanjun Guo Pamela M. Rist Iyas Daghlas Franco Giulianini The International Headache Genetics Consortium The 23andMe Research Team Tobias Kurth Daniel I. Chasman |
author_sort |
Yanjun Guo |
title |
A genome-wide cross-phenotype meta-analysis of the association of blood pressure with migraine |
title_short |
A genome-wide cross-phenotype meta-analysis of the association of blood pressure with migraine |
title_full |
A genome-wide cross-phenotype meta-analysis of the association of blood pressure with migraine |
title_fullStr |
A genome-wide cross-phenotype meta-analysis of the association of blood pressure with migraine |
title_full_unstemmed |
A genome-wide cross-phenotype meta-analysis of the association of blood pressure with migraine |
title_sort |
genome-wide cross-phenotype meta-analysis of the association of blood pressure with migraine |
publisher |
Nature Portfolio |
publishDate |
2020 |
url |
https://doaj.org/article/092c8891a7dd4e40a00ccb51a6c45afa |
work_keys_str_mv |
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