A genome-wide cross-phenotype meta-analysis of the association of blood pressure with migraine

A genome-wide cross-phenotype meta-analysis of the association of blood pressure with migraine

The association between blood pressure (BP) and migraine is poorly understood. Here, the authors explore this relationship using summary-level GWAS data for BP and migraine. Cross-trait meta-analysis reveals shared loci between BP and migraine, while Mendelian randomization suggests that diastolic B...

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Main Authors: Yanjun Guo, Pamela M. Rist, Iyas Daghlas, Franco Giulianini, The International Headache Genetics Consortium, The 23andMe Research Team, Tobias Kurth, Daniel I. Chasman
Format: article
Language:EN
Published: Nature Portfolio 2020
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Science
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Online Access:https://doaj.org/article/092c8891a7dd4e40a00ccb51a6c45afa
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spelling oai:doaj.org-article:092c8891a7dd4e40a00ccb51a6c45afa2021-12-02T15:39:43ZA genome-wide cross-phenotype meta-analysis of the association of blood pressure with migraine10.1038/s41467-020-17002-02041-1723https://doaj.org/article/092c8891a7dd4e40a00ccb51a6c45afa2020-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-17002-0https://doaj.org/toc/2041-1723The association between blood pressure (BP) and migraine is poorly understood. Here, the authors explore this relationship using summary-level GWAS data for BP and migraine. Cross-trait meta-analysis reveals shared loci between BP and migraine, while Mendelian randomization suggests that diastolic BP specifically plays a key role in migraine susceptibility.Yanjun GuoPamela M. RistIyas DaghlasFranco GiulianiniThe International Headache Genetics ConsortiumThe 23andMe Research TeamTobias KurthDaniel I. ChasmanNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Yanjun Guo
Pamela M. Rist
Iyas Daghlas
Franco Giulianini
The International Headache Genetics Consortium
The 23andMe Research Team
Tobias Kurth
Daniel I. Chasman
A genome-wide cross-phenotype meta-analysis of the association of blood pressure with migraine
description The association between blood pressure (BP) and migraine is poorly understood. Here, the authors explore this relationship using summary-level GWAS data for BP and migraine. Cross-trait meta-analysis reveals shared loci between BP and migraine, while Mendelian randomization suggests that diastolic BP specifically plays a key role in migraine susceptibility.
format article
author Yanjun Guo
Pamela M. Rist
Iyas Daghlas
Franco Giulianini
The International Headache Genetics Consortium
The 23andMe Research Team
Tobias Kurth
Daniel I. Chasman
author_facet Yanjun Guo
Pamela M. Rist
Iyas Daghlas
Franco Giulianini
The International Headache Genetics Consortium
The 23andMe Research Team
Tobias Kurth
Daniel I. Chasman
author_sort Yanjun Guo
title A genome-wide cross-phenotype meta-analysis of the association of blood pressure with migraine
title_short A genome-wide cross-phenotype meta-analysis of the association of blood pressure with migraine
title_full A genome-wide cross-phenotype meta-analysis of the association of blood pressure with migraine
title_fullStr A genome-wide cross-phenotype meta-analysis of the association of blood pressure with migraine
title_full_unstemmed A genome-wide cross-phenotype meta-analysis of the association of blood pressure with migraine
title_sort genome-wide cross-phenotype meta-analysis of the association of blood pressure with migraine
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/092c8891a7dd4e40a00ccb51a6c45afa
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