Learning a genome-wide score of human–mouse conservation at the functional genomics level

Understanding conserved functional genomic properties between human and mouse provides important context for mouse model studies. Here, the authors present a genome-wide conservation score integrating epigenomic, transcription factor binding, and transcriptomic data from mouse and human genomes.

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Detalles Bibliográficos
Autores principales:	Soo Bin Kwon, Jason Ernst
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/0932a4110b8849139c03740e978a6ce1
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spelling	oai:doaj.org-article:0932a4110b8849139c03740e978a6ce12021-12-02T16:49:12ZLearning a genome-wide score of human–mouse conservation at the functional genomics level10.1038/s41467-021-22653-82041-1723https://doaj.org/article/0932a4110b8849139c03740e978a6ce12021-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-22653-8https://doaj.org/toc/2041-1723Understanding conserved functional genomic properties between human and mouse provides important context for mouse model studies. Here, the authors present a genome-wide conservation score integrating epigenomic, transcription factor binding, and transcriptomic data from mouse and human genomes.Soo Bin KwonJason ErnstNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Soo Bin Kwon Jason Ernst Learning a genome-wide score of human–mouse conservation at the functional genomics level
description	Understanding conserved functional genomic properties between human and mouse provides important context for mouse model studies. Here, the authors present a genome-wide conservation score integrating epigenomic, transcription factor binding, and transcriptomic data from mouse and human genomes.
format	article
author	Soo Bin Kwon Jason Ernst
author_facet	Soo Bin Kwon Jason Ernst
author_sort	Soo Bin Kwon
title	Learning a genome-wide score of human–mouse conservation at the functional genomics level
title_short	Learning a genome-wide score of human–mouse conservation at the functional genomics level
title_full	Learning a genome-wide score of human–mouse conservation at the functional genomics level
title_fullStr	Learning a genome-wide score of human–mouse conservation at the functional genomics level
title_full_unstemmed	Learning a genome-wide score of human–mouse conservation at the functional genomics level
title_sort	learning a genome-wide score of human–mouse conservation at the functional genomics level
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/0932a4110b8849139c03740e978a6ce1
work_keys_str_mv	AT soobinkwon learningagenomewidescoreofhumanmouseconservationatthefunctionalgenomicslevel AT jasonernst learningagenomewidescoreofhumanmouseconservationatthefunctionalgenomicslevel
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Learning a genome-wide score of human–mouse conservation at the functional genomics level

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